LOCUS       SIT99695.1               671 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 pe-
            pgrs family protein pe_pgrs19 protein.
ACCESSION   LT708304-1107
PROTEIN_ID  SIT99695.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PE_PGRS19"
                     /locus_tag="BQ2027_MB1096C"
                     /note="Mb1096c, PE_PGRS19, len: 671 aa. Equivalent to
                     Rv1067c, len: 667 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (98.5% identity in 673 aa overlap). Member
                     of the Mycobacterium tuberculosis PE family, PGRS
                     subfamily of gly-rich proteins. Similar to
                     Rv3388|MTV004.46 from Mycobacterium tuberculosis (731 aa),
                     FASTA scores: opt: 2227, E(): 0, (55.6% identity in 710 aa
                     overlap). Contains PS00583 pfkB family of carbohydrate
                     kinases signature 1, probably fortuitous.
                     REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, 2
                     deletions each of 3 bp (ccg-* and cgc-*) and a 18 bp
                     insertion leads to a longer product compared to its
                     homolog in Mycobacterium tuberculosis strain H37Rv (671 aa
                     versus 667 aa)."
                     /db_xref="InterPro:IPR000084"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XXL9"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MSFVLVSPSQ LMAAAADVAG IGSAISAANA AALAPTSVLA AAGADEVSAA VAALFSAHAG
       61 QYQQLGARAA LFHEQFVQAL TGAASAYASA EATNVEQQVL GLINAPTQAL WGRPLIGNGA
      121 DGTAANPNGG AGGLLYGNGG NGFSQTTAGL TGGTGGSAGL IGNGGNGGAG GAGANGGAGG
      181 NGGWLYGSGG NGGAGGAGPA GAIGAPGVAG GAGGAGGTAG LFGNGGVGGV GGDGGQGGNG
      241 AGAGASGTKG GDAGAGGAGG AGGWIHGHGG AGGDGGAGGA GGQASPGAPG PPSQPGGAGG
      301 AGGAGGRGGD GGSAGWLSGN GGDAGNGGGG GTAGGAGNGG QFGGDGGTGG TGGTAGAGGN
      361 GGRGAVLFGH GGNAGHGGAG GNGAAAGAGG EHVMATAGKG GTGGVGGDGG GGAGGGGGLL
      421 YGNGGAGGNG GAGGAGNSGG DGGTGLNAAL GGNGGGGGVG GNAGAGGTGG SAGWLSGNGG
      481 AGGSGGSAGA GGAGGKGGDT PNGLAINPGI GGNGGDTGNA GNGGNGGSAA RLFGGGGAGG
      541 AGGTGSTAGS GGSGGTNPPT GLQAAGGNGG SGHAGGHGGN GGGAGLLGGG TGGNGGGGGQ
      601 GGLGAAAGGV DGNGGNGGNG GKGGDAQLVG DGGNGGNGGK GGAGLIAGLD GAGGAGGTRG
      661 LIFGNAGTPG Q
//