LOCUS       SIT99643.1               252 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 probable
            conserved lipoprotein lpqt protein.
ACCESSION   LT708304-1055
PROTEIN_ID  SIT99643.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lpqT"
                     /locus_tag="BQ2027_MB1044C"
                     /note="Mb1044c, lpqT, len: 252 aa. Equivalent to 5' end of
                     Rv1016c, len: 226 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (98.9% identity in 190 aa overlap). Probable
                     lpqT, conserved lipoprotein. Similar to several M.
                     tuberculosis hypothetical proteins e.g.
                     Rv0040c|Y0H3_MYCTU|P71697 Proline rich 28 kDA antigen (310
                     aa), FASTA scores: opt: 329, E(): 2e-17, (32.3% identity
                     in 229 aa overlap); Rv0583c. Contains PS00013 Prokaryotic
                     membrane lipoprotein lipid attachment site.
                     REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a
                     frameshift due to a 5 bp deletion (cacgc-*) leads to a
                     longer product with a different COOH part compared to its
                     homolog in Mycobacterium tuberculosis strain H37Rv.
                     Protein product from Mb1044c detected using SWATH mass
                     spectrometry. Mb1044c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:Q7U0V0"
                     /db_xref="InterPro:IPR019674"
                     /db_xref="UniProtKB/Swiss-Prot:Q7U0V0"
BEGIN
        1 MAGRRCPQDS VRPLAVAVAV ATLAMSAVAC GPKSPDFQSI LSTSPTTSAV STTTEVPVPL
       61 WKYLESVGVT GEPVAPSSLT DLTVSIPTPP GWAPMKNPNI TPNTEMIAKG ESYPTAMLMV
      121 FKLHRDFDIA EALKHGTADA RLSTNFTELD SSTADFNGFP SSMIQGSYDL HGRRLHTWNR
      181 IVFPTGAGQA ALPGAAHHHE SGQRGRQARF RHRGDHRRIR RRGKVIVRTV GAQLSEQLTR
      241 IEFPQCSSHG LA
//