LOCUS SIT99516.1 393 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY LUXR-FAMILY) protein. ACCESSION LT708304-928 PROTEIN_ID SIT99516.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0918" /note="Mb0918, -, len: 393 aa. Equivalent to Rv0894, len: 393 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 393 aa overlap). Possible regulatory protein, LuxR family, highly similar in part to NP_302202.1|NC_002677 possible transcriptional regulator from Mycobacterium leprae (1106 aa). Also similar to others e.g. CAB95788.1|AL359949 putative multi-domain regulatory protein from Streptomyces coelicolor (780 aa); NP_107293.1|NC_002678 transcriptional regulator from Mesorhizobium loti (903 aa); etc. Also similar to other regulatory proteins from Mycobacterium tuberculosis e.g. Rv2488c|MTV008_44 (1137 aa), FASTA score: (53.2% identity in 363 aa overlap); Rv1358|MTCY02B10_22 (1159 aa), FASTA score: (52.3% identity in 365 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop)." /db_xref="GOA:P64750" /db_xref="InterPro:IPR027417" /db_xref="UniProtKB/Swiss-Prot:P64750" BEGIN 1 MPSRATVQEF SDSYPFCHNG FRPIMMPKIV SVQHSTRRHL TSFVGRKAEL NDVRRLLSDK 61 RLVTLTGPDG MGKSRLALQI GAQIAHEFTY GRWDCDLATV TDRDCVSISM LNALGLPVQP 121 GLSAIDTLVG VINDARVLLV LDHCEHLLDA CAAIIDSLLR SCPRLTILTT STEAIGLAGE 181 LTWRVPPLSL TNDAIELFVD RARRVRSDFA INADTAVTVG EICRRLDGVP LAIELAAART 241 DTLSPVEILA GLNDRFRLVA GAAGNAVRPE QTLCATVQWS HALLSGPERA LLHRLAVFAG 301 GFDLDGAQAV GANDEDFEGY QTLGRFAELV DKAFVVVENN RGRAGYRLLY SVRQYALEKL 361 SESGEADAVL ARYRKHLKQP NQVVRAGSGG VRY //