LOCUS       SIT99480.1               397 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 probable
            n-succinyldiaminopimelate aminotransferase dapc (dap-at)
            protein.
ACCESSION   LT708304-892
PROTEIN_ID  SIT99480.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="dapc"
                     /locus_tag="BQ2027_MB0881C"
                     /note="Mb0881c, -, len: 397 aa. Equivalent to Rv0858c,
                     len: 397 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 397 aa overlap). Probable
                     aminotransferase (EC 2.6.1.-), highly similar to others
                     from Eukaryota and bacteria, especially aspartate
                     aminotransferases (transaminases) (EC 2.6.1.1), e.g.
                     NP_177890.1|NC_003070 putative aminotransferase from
                     Arabidopsis thaliana (440 aa); NP_419555.1|NC_002696
                     aminotransferase class I from Caulobacter crescentus (385
                     aa); NP_415133.1|NC_000913|AE0001|ECAE000165_8 putative
                     aminotransferase from Escherichia coli strain K12 (386
                     aa), FASTA scores: opt: 830, E(): 0, (38.0% identity in
                     389 aa overlap); X99521|TAX99521_1 aspartate
                     aminotransferase from Thermus aquaticus (383 aa), FASTA
                     scores: opt: 702, E(): 0, (34.9% identity in 393 aa
                     overlap); etc. Also similar to other putative
                     aminotransferases from Mycobacterium tuberculosis e.g.
                     Rv2294, Rv3565, etc. Protein product from Mb0881c detected
                     using SWATH mass spectrometry. Mb0881c found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3XWP0"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWP0"
BEGIN
        1 MTVSRLRPYA TTVFAEMSAL ATRIGAVNLG QGFPDEDGPP KMLQAAQDAI AGGVNQYPPG
       61 PGSAPLRRAI AAQRRRHFGV DYDPETEVLV TVGATEAIAA AVLGLVEPGS EVLLIEPFYD
      121 SYSPVVAMAG AHRVTVPLVP DGRGFALDAD ALRRAVTPRT RALIINSPHN PTGAVLSATE
      181 LAAIAEIAVA ANLVVITDEV YEHLVFDHAR HLPLAGFDGM AERTITISSA AKMFNCTGWK
      241 IGWACGPAEL IAGVRAAKQY LSYVGGAPFQ PAVALALDTE DAWVAALRNS LRARRDRLAA
      301 GLTEIGFAVH DSYGTYFLCA DPRPLGYDDS TEFCAALPEK VGVAAIPMSA FCDPAAGQAS
      361 QQADVWNHLV RFTFCKRDDT LDEAIRRLSV LAERPAT
//