LOCUS       SIT99479.1               157 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 link
            to Polyketide_cyclase/dehydratase. protein.
ACCESSION   LT708304-891
PROTEIN_ID  SIT99479.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0880"
                     /note="Mb0880, -, len: 157 aa. Equivalent to Rv0857, len:
                     157 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 157 aa overlap). Conserved
                     hypothetical protein, showing weak similarity with
                     SC6G10.02|T35511 hypothetical protein from Streptomyces
                     coelicolor (144 aa). Also highly similar to other proteins
                     from Mycobacterium tuberculosis e.g. upstream ORF Rv0856
                     (134 aa), FASTA scores: E(): 9.6e-28, (61.6% identity in
                     99 aa overlap); upstream ORF Rv0854 (147 aa), FASTA
                     scores: E(): 2.8e-18, (42.7% identity in 117 aa overlap);
                     MTCI28.04|Z97050 (184 aa), FASTA scores: opt: 122, E():
                     0.031, (29.4% identity in 85 aa overlap); and
                     MLCL622.27c|Z95398 (156 aa), FASTA scores: opt: 114, E():
                     0.1, (30.9% identity in 55 aa overlap). Protein product
                     from Mb0880 detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb0880 found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR019587"
                     /db_xref="InterPro:IPR023393"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XWM9"
BEGIN
        1 MIANLVAVAI RASREVVIEA PPEVIVEALA DMDAVPSWSS VHKRVEVVDT YSDGRPHHVK
       61 VTIKVAGIVD TELLEYHWGP DWVVWDAAKT AQQHGQHGEY NLRREDNDKT RVRFTLTVEP
      121 SAPLPAFWVN IARKKILHAA TEGLRKQVVG RRRFTSG
//