LOCUS       SIT99314.1               470 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            MEMBRANE SUGAR TRANSFERASE protein.
ACCESSION   LT708304-726
PROTEIN_ID  SIT99314.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0715"
                     /note="Mb0715, -, len: 470 aa. Equivalent to Rv0696, len:
                     470 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 470 aa overlap). Probable membrane
                     sugar transferase (EC 2.-.-.-), similar (except in
                     N-terminus) to NP_069157.1|NC_000917 glycosyl transferase
                     from Archaeoglobus fulgidus (324 aa);
                     NP_279985.1|NC_002607 rhamnosyl transferase from
                     Halobacterium sp. NRC-1 (299 aa); NP_059113.1|NM_017417
                     polypeptide N-acetylgalactosaminyltransferase 8 from (637
                     aa). Note that also highly similar to P46370|YTH1_RHOER
                     HYPOTHETICAL 55.3 KDA PROTEIN from Rhodococcus
                     erythropolis (513 aa), FASTA scores: opt: 1514, E(): 0,
                     (51.8% identity in 469 aa overlap). Protein product from
                     Mb0715 detected using SWATH mass spectrometry. Mb0715
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XW90"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR023981"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XW90"
BEGIN
        1 MTATRLPDGF AVQVDRRVRV LGDGSALLGG SPTRLLRLAP AARGLLCDGR LKVRDEVSAE
       61 LARILLDATV AHPRPPSGPS HRDVTVVIPV RNNASGLRRL VTSLRGLRVI VVDDGSACPV
      121 ESDDFVGAHC DIEVLHHPHS KGPAAARNTG LAACTTDFVA FLDSDVTPRR GWLESLLGHF
      181 CDPTVALVAP RIVSLVEGEN PVARYEALHS SLDLGQREAP VLPHSTVSYV PSAAIVCRSS
      241 AIRDVGGFDE TMHSGEDVDL CWRLIEAGAR LRYEPIALVA HDHRTQLRDW IARKAFYGGS
      301 AAPLAVRHPD KTAPLVISGG ALMAWILMSI GTGLGRLASL VIAVLTGRRI ARAMRCAETS
      361 FLDVLAVATR GLWAAALQLA SAICRHYWPL ALLAAILSRR CRRVVLIAAV VDGVVDWLRR
      421 REGADDDAEP IGPLTYLVLK RVDDLAYGAG LWYGVVRERN IGALKPQIRT
//