LOCUS SIT99218.1 247 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 possible transposase (fragment) protein. ACCESSION LT708304-630 PROTEIN_ID SIT99218.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0622" /note="Mb0622, -, len: 247 aa. Equivalent to Rv0606, len: 247 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 247 aa overlap). Possible truncated transposase for IS_1536 element, highly similar to N-terminus of other transposases from Mycobacterium tuberculosis e.g. YX16_MYCTU|Q10809|Rv2885c|MT2953|MTCY274 .16c PUTATIVE TRANSPOSASE from Mycobacterium tuberculosis (460 aa), FASTA scores: opt: 1368, E(): 0, (83.5% identity in 237 aa overlap); Rv2978c, Rv0922, Rv3827c, etc. Also similar to N-terminus of MTV002_57|Rv2792 RESOLVASE from M. tuberculosis (193 aa), FASTA score: (87.4% identity in 238 aa overlap). Mb0622 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR021027" /db_xref="UniProtKB/TrEMBL:A0A1R3XVV9" BEGIN 1 MPRLEIPNGW CVQAFRFTLD PTAEQAHALA RHFGARRKAY NWTVAQLKAD IQAWRATGAQ 61 TAKPSLRVLR KRWNTVKDEV CVNAETGTVW WPECSKEAYA DGIAGAVDAY WNWQQRRAGK 121 RDGKRMGFPR FKKKGRDADR VSFTTGAMRV EPDRRHLTLP VIGCVRTHEN TRRIERLIAK 181 DRARVLAITV RRNGTRLDAS VRVLVQRPQQ PNVELPESRI GVDVGVRRLA TVATADGACC 241 PVLVPDG //