LOCUS SIT98446.1 303 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE OXIDOREDUCTASE protein. ACCESSION LT708304-70 PROTEIN_ID SIT98446.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0069" /note="Mb0069, -, len: 303 aa. Equivalent to Rv0068, len: 303 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 303 aa overlap). Probable oxidoreductase (EC 1.-.-.-), equivalent to NP_301343.1|NC_002677 putative oxidoreductase from Mycobacterium leprae (304 aa). Also highly similar to many e.g. NP_485762.1|NC_003272 probable oxidoreductase from Nostoc sp. PCC 7120 (311 aa); NP_279536.1|NC_002607|YajO1 probable oxidoreductase from Halobacterium sp. NRC-1 (316 aa); OXIR_STRAT|Q03326 probable oxidoreductase from Streptomyces antibioticus (298 aa), FASTA scores: opt: 430, E(): 1.3e-16, (34.9% identity in 295 aa overlap); etc. Also highly similar to MTV037_3 and MTV022_13 from Mycobacterium tuberculosis. Protein product from Mb0069 detected using shotgun mass spectrometry and SWATH mass spectrometry." /db_xref="InterPro:IPR002347" /db_xref="InterPro:IPR036291" /db_xref="UniProtKB/TrEMBL:A0A1R3XUE4" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MTKWTAADIP DQTGRTAVIT GANTGLGFET AAALAAHGAH VVLAVRNLDK GKQAAARITE 61 ATPGAEVELQ ELDLTSLASV RAAAAQLKSD HQRIDLLINN AGVMYTPRQT TADGFEMQFG 121 TNHLGHFALT GLLIDRLLPV AGSRVVTISS VGHRIRAAIH FDDLQWERRY RRVAAYGQAK 181 LANLLFTYEL QRRLAPGGTT IAVASHPGVS NTELVRNMPR PLVAVAAILA PLMQDAELGA 241 LPTLRAATDP AVRGGQYFGP DGFGEIRGYP KVVASSAQSH DEQLQRRLWA VSEELTGVVY 301 PVG //