LOCUS       SIT98405.1               264 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            OXIDOREDUCTASE protein.
ACCESSION   LT708304-45
PROTEIN_ID  SIT98405.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0045C"
                     /note="Mb0045c, -, len: 264 aa. Equivalent to Rv0044c,
                     len: 264 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 264 aa overlap). Possible
                     oxidoreductase (EC 1.-.-.-), highly similar to
                     AAD32732.1|MmcI|AF127374| F420-dependent H4MPT reductase
                     from Streptomyces lavendulae (264 aa). Also similar to
                     Mycobacterium tuberculosis proteins e.g. Rv1855c, Rv0953c,
                     Rv0791c, Rv0132c, etc. Protein product from Mb0045c
                     detected using shotgun mass spectrometry. Mb0045c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XU55"
                     /db_xref="InterPro:IPR011251"
                     /db_xref="InterPro:IPR022480"
                     /db_xref="InterPro:IPR036661"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XU55"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTSLVRPDLP VRIGVQLQPQ HAPHYRAVRD AVRRCEDIGV DIAFTWDHFF PLYGDPDGPH
       61 FECWTVLGAW AEQTSHIEIG ALVTCNSYRN PELLADMART VDHISGGRLI LGIGSGWKQK
      121 DYDEYGYRFG TAGSRLDDLA AALPRIKARL GKLNPPPTRD IPVLIGGGGE RKTLRLVAEY
      181 ADIWHSFTAG DSYLAKSAVL STHCSTVGRN PATIERSAAV DGGGLIASAE ALAGLGVTLL
      241 TVGCDGPDYD LSAAAALCRW RDGR
//