LOCUS SIT60429.1 905 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Ligand-Gated ion Channel protein. ACCESSION BX284602-1295 PROTEIN_ID SIT60429.1 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 15279421) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 15279421) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 15279421) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="II" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="lgc-45" /locus_tag="CELE_W10G11.16" /standard_name="W10G11.16c" /note="Product from WormBase gene class lgc" /note="Confirmed by transcript evidence" /db_xref="GOA:A0A1N7SYR3" /db_xref="InterPro:IPR006028" /db_xref="InterPro:IPR006029" /db_xref="InterPro:IPR006201" /db_xref="InterPro:IPR006202" /db_xref="InterPro:IPR018000" /db_xref="InterPro:IPR036719" /db_xref="InterPro:IPR036734" /db_xref="UniProtKB/TrEMBL:A0A1N7SYR3" /db_xref="WormBase:WBGene00021146" intron_pos 31:0 (1/14) intron_pos 85:0 (2/14) intron_pos 126:0 (3/14) intron_pos 193:0 (4/14) intron_pos 299:2 (5/14) intron_pos 387:0 (6/14) intron_pos 429:2 (7/14) intron_pos 484:1 (8/14) intron_pos 530:2 (9/14) intron_pos 580:0 (10/14) intron_pos 653:2 (11/14) intron_pos 681:1 (12/14) intron_pos 763:0 (13/14) intron_pos 805:0 (14/14) BEGIN 1 MDYNLSTDDF EECATWQKYW NLTAELEKNK DRNLSSSGND TEDVVSEIDE LKETEENLKQ 61 TELVNTKNRL KALGLNPELL VAYKAVGLVY REICGNHGRT LWYRTREDAS LIGVDSFSPI 121 CEPFKEQLNP DESTLSQLAL KLNILIQNVT EGFEPALRRG GGGNTTSTED GEIQNSTMLT 181 SKEPEAVTSD DSIVLLPSST DSSKEQLTTS HPAHHHHHHH HHQHHQTPPA PSTETPETPT 241 TAQQADYEIN DDEYDNRVFS SGLPPEEPTT TTEPTTTTTE SISEVEVYDD DVWDYRDMEK 301 RFKVRHQVVF DGNEIGEDEL DGSFPSIHQA SNRKRRRHVV LKTKIRRRRR RKRAAGSDEE 361 DEKKSSETVI DVHQDSGEND EDWLNVRQVI KTTDGETTVA IIEERSHLLD GNSTDVRAWI 421 EIDASDLINP TLLISSPEAV AALGLEVEAT AFQRFENVGL YLPGICSEYV PKAIDEFNSS 481 SFEGIEIEGP IGVNITALEL AGVNLTSLAD KLRNDTEVDE ILSRTNGSTK NLGGSFILPV 541 LNKNQYDPFS APIVFQGSAV VVRFGIYIES MSNFQTSTMD YDMDIYLMMS WRDARLVNPY 601 DKPILVKEED ILEKIWRPDP FFANAKEAEF HEVTFLNFLM RIFPDGLVLY ETRVKIKPSC 661 NLILCKYPHD KQTCDLLIKS FAYPVETVRF EWFTRRKDAI DKNPDVKLPE LYIDRYETTT 721 CPNERKSGAF SCLRAVFRLK RDVGFHIAQT YIPTSLALMF SWVGVWLPEE FMEGRIGVAI 781 TVLLTLSTES AGAREHLPSV SYLKAIDLWF GFITGFVFFT LLQTLFVIGF DKRANQLKKW 841 AGRKTADITE EIREALLQKA TRYHKTGRYL DNFCRVFYPL SFILFLLMYY FVFTEGRQDD 901 CMNRR //