LOCUS CCP46391.1 300 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv 3,4-DHSA dioxygenase protein. ACCESSION AL123456-3669 PROTEIN_ID CCP46391.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /gene="hsaC" /gene_synonym="bphC" /locus_tag="Rv3568c" /note="Rv3568c, (MTCY06G11.15c), len: 300 aa. HsaC, highly similar to e.g. Q9KWQ5|BPHC5 from Rhodococcus sp. RHA1 (300 aa), FASTA scores: opt: 1715, E(): 3.8e-103, (82.15% identity in 297 aa overlap); O50479|EDOB from Rhodococcus rhodochrous (300 aa) FASTA scores: opt: 1714, E(): 4.4e-103, (82.5% identity in 297 aa overlap); O69359|BPHC6 from Rhodococcus erythropolis (300 aa), FASTA scores: opt: 1647, E(): 9.1e-99, (78.25% identity in 299 aa overlap); Q9RBT2|BPHC1 from Pseudomonas sp. SY5 (301 aa) Pseudomonas sp. SY5 (298 aa) FASTA scores: opt: 767, E(): 3.9e-42,(42.8% identity in 299 aa overlap); P47228|BPHC_BURCE from Burkholderia cepacia (Pseudomonas cepacia) (297 aa), FASTA scores: opt: 670, E(): 6.8e-36, (40.55% identity in 296 aa overlap); etc. Contains PS00082 Extradiol ring-cleavage dioxygenases signature. Belongs to the extradiol ring-cleavage dioxygenase family." /db_xref="EnsemblGenomes-Gn:Rv3568c" /db_xref="EnsemblGenomes-Tr:CCP46391" /db_xref="GOA:P9WNW7" /db_xref="InterPro:IPR000486" /db_xref="InterPro:IPR004360" /db_xref="InterPro:IPR029068" /db_xref="InterPro:IPR037523" /db_xref="PDB:2ZI8" /db_xref="PDB:2ZYQ" /db_xref="UniProtKB/Swiss-Prot:P9WNW7" /inference="protein motif:PROSITE:PS00082" /experiment="EXISTENCE: identified in proteomics study" BEGIN 1 MSIRSLGYLR IEATDMAAWR EYGLKVLGMV EGKGAPEGAL YLRMDDFPAR LVVVPGEHDR 61 LLEAGWECAN AEGLQEIRNR LDLEGTPYKE ATAAELADRR VDEMIRFADP SGNCLEVFHG 121 TALEHRRVVS PYGHRFVTGE QGMGHVVLST RDDAEALHFY RDVLGFRLRD SMRLPPQMVG 181 RPADGPPAWL RFFGCNPRHH SLAFLPMPTS SGIVHLMVEV EQADDVGLCL DRALRRKVPM 241 SATLGRHVND LMLSFYMKTP GGFDIEFGCE GRQVDDRDWI ARESTAVSLW GHDFTVGARG //