LOCUS       CCP46379.1               200 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Transcriptional regulatory
            protein (probably TetR-family) protein.
ACCESSION   AL123456-3657
PROTEIN_ID  CCP46379.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /locus_tag="Rv3557c"
                     /note="Rv3557c, (MTCY06G11.04c), len: 200 aa.
                     Transcriptional regulator, TetR family, similar to other
                     e.g. Q9RRV9|DR2376 from Deinococcus radiodurans (197 aa)
                     FASTA scores: opt: 326, E(): 2.3e-14, (31.2% identity in
                     189 aa overlap); Q9HZW2|PA2885 from Pseudomonas aeruginosa
                     (198 aa), FASTA scores: opt: 308, E(): 3.5e-13, (31.55%
                     identity in 187 aa overlap); Q9RFR4 from Pseudomonas
                     fluorescens (207 aa), FASTA scores: opt: 291, E():
                     4.7e-12,(29.75% identity in 195 aa overlap); Q9K8P5|BH2958
                     from Bacillus halodurans (215 aa), FASTA scores: opt: 271,
                     E(): 9.9e-11, (23.95% identity in 192 aa overlap); etc.
                     Also similar to proteins from Mycobacterium tuberculosis
                     e.g. O53641|Rv0158|MTV032.01 (214 aa), FASTA scores: opt:
                     232,E(): 3.5e-08, (25.5% identity in 192 aa overlap); and
                     O06169|Rv2506|MTCY07A7.12 (215 aa), FASTA scores: opt:
                     215,E(): 4.5e-07, (35.15% identity in 148 aa overlap);
                     etc. Seems to belong to the TetR/AcrR family of
                     transcriptional regulators."
                     /db_xref="EnsemblGenomes-Gn:Rv3557c"
                     /db_xref="EnsemblGenomes-Tr:CCP46379"
                     /db_xref="GOA:P9WMB9"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR036271"
                     /db_xref="InterPro:IPR041490"
                     /db_xref="PDB:4W1U"
                     /db_xref="PDB:4W97"
                     /db_xref="UniProtKB/Swiss-Prot:P9WMB9"
BEGIN
        1 MDRVAGQVNS RRGELLELAA AMFAERGLRA TTVRDIADGA GILSGSLYHH FASKEEMVDE
       61 LLRGFLDWLF ARYRDIVDST ANPLERLQGL FMASFEAIEH HHAQVVIYQD EAQRLASQPR
      121 FSYIEDRNKQ QRKMWVDVLN QGIEEGYFRP DLDVDLVYRF IRDTTWVSVR WYRPGGPLTA
      181 QQVGQQYLAI VLGGITKEGV
//