LOCUS       CCP44991.1               592 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Possible short-chain
            dehydrogenase EphD protein.
ACCESSION   AL123456-2269
PROTEIN_ID  CCP44991.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="ephD"
                     /locus_tag="Rv2214c"
                     /note="Rv2214c, (MTCY190.25c), len: 592 aa. Possible
                     ephD,short-chain dehydrogenase (see citation below),
                     equivalent to Z98741|MLCB22_8 Mycobacterium leprae cosmid
                     B22; (596 aa), FASTA score: opt: 3262, E(): 0; 80.4%
                     identity in 596 aa overlap. C-terminus similar to
                     short-chain alcohol dehydrogenase family, similar to
                     SW:LIGD_PSEPA Q01198 c alpha-dehydrogenase (30.7% identity
                     in 241 aa overlap); contains PS00061 Short-chain alcohol
                     dehydrogenase family signature, PS00697 ATP-dependent DNA
                     ligase AMP-binding site. N-terminus corresponds to several
                     epoxide hydrolases of plants and Mycobacterium
                     tuberculosis e.g. MTCY9F925"
                     /db_xref="EnsemblGenomes-Gn:Rv2214c"
                     /db_xref="EnsemblGenomes-Tr:CCP44991"
                     /db_xref="GOA:P9WGS3"
                     /db_xref="InterPro:IPR000073"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="UniProtKB/Swiss-Prot:P9WGS3"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MPATQQMSRL VDSPDGVRIA VYHEGNPDGP TVVLVHGFPD SHVLWDGVVP LLAERFRIVR
       61 YDNRGVGRSS VPKPISAYTM AHFADDFDAV IGELSPGEPV HVLAHDWGSV GVWEYLRRPG
      121 ASDRVASFTS VSGPSQDHLV NYVYGGLRRP WRPRTFLRAI SQTLRLSYMA LFSVPVVAPL
      181 LLRVALSSAA VRRNMVGDIP VDQIHHSETL ARDAAHSVKT YPANYFRSFS SSRRGRAIPI
      241 VDVPVQLIVN SQDPYVRPYG YDQTARWVPR LWRRDIKAGH FSPMSHPQVM AAAVHDFADL
      301 ADGKQPSRAL LRAQVGRPRG YFGDTLVSVT GAGSGIGRET ALAFAREGAE IVISDIDEAT
      361 VKDTAAEIAA RGGIAYPYVL DVSDAEAVEA FAERVSAEHG VPDIVVNNAG IGQAGRFLDT
      421 PAEQFDRVLA VNLGGVVNGC RAFGQRLVER GTGGHIVNVS SMAAYAPLQS LSAYCTSKAA
      481 TYMFSDCLRA ELDAAGVGLT TICPGVIDTN IVATTGFHAP GTDEEKIDGR RGQIDKMFAL
      541 RSYGPDKVAD AIVSAVKKKK PIRPVAPEAY ALYGISRVLP QALRSTARLR VI
//