LOCUS       CCP44916.1               448 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Conserved protein protein.
ACCESSION   AL123456-2194
PROTEIN_ID  CCP44916.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene_synonym="dapE2"
                     /locus_tag="Rv2141c"
                     /note="Rv2141c, (MTCY270.27), len: 448 aa. Conserved
                     protein. Shows some similarity to conserved hypothetical
                     proteins and to acetylornithine deacetylase and
                     succinyl-diaminopimelate desuccinylase and contains
                     ArgE/dapE/ACY1/CPG2/yscS family signature 1 (PS00758).
                     FASTA best: CBPS_YEAST P27614 carboxypeptidases precursor
                     (576 aa) opt: 234, E(): 4.3e-08; (24.3% identity in 412 aa
                     overlap). Previously named dapE2. Conserved in M.
                     tuberculosis, M. leprae, M. bovis and M. avium
                     paratuberculosis; predicted to be essential for in vivo
                     survival and pathogenicity (See Ribeiro-Guimaraes and
                     Pessolani, 2007)."
                     /db_xref="EnsemblGenomes-Gn:Rv2141c"
                     /db_xref="EnsemblGenomes-Tr:CCP44916"
                     /db_xref="GOA:L7N684"
                     /db_xref="InterPro:IPR001261"
                     /db_xref="InterPro:IPR002933"
                     /db_xref="InterPro:IPR011650"
                     /db_xref="InterPro:IPR036264"
                     /db_xref="UniProtKB/TrEMBL:L7N684"
                     /inference="protein motif:PROSITE:PS00758"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MTDETGASSD HSDDVAQVVS RLIRFDTTNS GEPGTTKGEA ECARWVAEQL AEVGYQPEYV
       61 ESGAPGRGNV FARLAGADSS RGALLIHGHL DVVPAEPAEW SVHPFSGAIE DGYVWGRGAV
      121 DMKDMVGMMI VVARHLRQAA IVPPRDLVFA FVADEEHGGK YGSHWLVDNR PDLFDGITEA
      181 IGEVGGFSLT VPRHDGGERR LYLIETAEKG IQWMRLTARG RAGHGSMVHD QNAVTAVCEA
      241 VARLGRHQFP LVCTDTVAQF LAVVGEETGL AFDLDSPDLA GTIDKLGPMA RMLKAVLHDT
      301 ANPTMLKAGY KANVVPATAE AVVDCRVLPG RRAAFEAEVD ALIGPDVTRE WVSDLPSYET
      361 TFDGDLVAAM NAAVLAVDPD GRTVPYMLSG GTDAKAFARL GIRCFGFSPL RLPPDLDFTS
      421 LFHGVDERVP IDGLRFGTEV LTHLLTHC
//