LOCUS CCP44012.1 405 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv Probable cytochrome P450 130 Cyp130 protein. ACCESSION AL123456-1290 PROTEIN_ID CCP44012.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /gene="cyp130" /locus_tag="Rv1256c" /note="Rv1256c, (MT1295, MTCY50.26), len: 405 aa. Probable cyp130, cytochrome P450, similar to other cytochromes P-450 e.g. S51594 cytochrome P450 mycG from Micromonospora griseorubida (397 aa); T36526 probable cytochrome P450 hydroxylase from Streptomyces coelicolor (411 aa); CPXK_SACER|P33271|107B1 cytochrome P450 from Saccharopolyspora erythraea (405 aa), FASTA scores: opt: 639, E(): 2.7e-33, (33.2% identity in 391 aa overlap); etc. Also similar to others from Mycobacterium tuberculosis e.g. Rv0766c|MTCY369.11c cytochrome P450 (402 aa); etc. Contains PS00086 Cytochrome P450 cysteine heme-iron ligand signature. Belongs to the cytochrome P450 family." /db_xref="EnsemblGenomes-Gn:Rv1256c" /db_xref="EnsemblGenomes-Tr:CCP44012" /db_xref="GOA:P9WPN5" /db_xref="InterPro:IPR001128" /db_xref="InterPro:IPR002397" /db_xref="InterPro:IPR017972" /db_xref="InterPro:IPR036396" /db_xref="PDB:2UUQ" /db_xref="PDB:2UVN" /db_xref="PDB:2WGY" /db_xref="PDB:2WH8" /db_xref="PDB:2WHF" /db_xref="UniProtKB/Swiss-Prot:P9WPN5" /inference="protein motif:PROSITE:PS00086" BEGIN 1 MTSVMSHEFQ LATAETWPNP WPMYRALRDH DPVHHVVPPQ RPEYDYYVLS RHADVWSAAR 61 DHQTFSSAQG LTVNYGELEM IGLHDTPPMV MQDPPVHTEF RKLVSRGFTP RQVETVEPTV 121 RKFVVERLEK LRANGGGDIV TELFKPLPSM VVAHYLGVPE EDWTQFDGWT QAIVAANAVD 181 GATTGALDAV GSMMAYFTGL IERRRTEPAD DAISHLVAAG VGADGDTAGT LSILAFTFTM 241 VTGGNDTVTG MLGGSMPLLH RRPDQRRLLL DDPEGIPDAV EELLRLTSPV QGLARTTTRD 301 VTIGDTTIPA GRRVLLLYGS ANRDERQYGP DAAELDVTRC PRNILTFSHG AHHCLGAAAA 361 RMQCRVALTE LLARCPDFEV AESRIVWSGG SYVRRPLSVP FRVTS //