LOCUS CCP43845.1 312 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv Probable pantothenate kinase CoaA (pantothenic acid kinase) protein. ACCESSION AL123456-1123 PROTEIN_ID CCP43845.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /gene="coaA" /locus_tag="Rv1092c" /note="Rv1092c, (MTV017.45c), len: 312 aa. Probable coaA,pantothenate kinase, similar to many e.g. P15044|COAA_ECOLI Escherichia coli (316 aa), FASTA scores :opt: 1079, E(): 0,(52.7% identity in 311 aa overlap). Equivalent to AL049491|MLCB1222_17 Mycobacterium leprae (312 aa) (93.6% identity in 312 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the pantothenate kinase family." /db_xref="EnsemblGenomes-Gn:Rv1092c" /db_xref="EnsemblGenomes-Tr:CCP43845" /db_xref="GOA:P9WPA7" /db_xref="InterPro:IPR004566" /db_xref="InterPro:IPR006083" /db_xref="InterPro:IPR027417" /db_xref="PDB:2GES" /db_xref="PDB:2GET" /db_xref="PDB:2GEU" /db_xref="PDB:2GEV" /db_xref="PDB:2ZS7" /db_xref="PDB:2ZS8" /db_xref="PDB:2ZS9" /db_xref="PDB:2ZSA" /db_xref="PDB:2ZSB" /db_xref="PDB:2ZSD" /db_xref="PDB:2ZSE" /db_xref="PDB:2ZSF" /db_xref="PDB:3AEZ" /db_xref="PDB:3AF0" /db_xref="PDB:3AF1" /db_xref="PDB:3AF2" /db_xref="PDB:3AF3" /db_xref="PDB:3AF4" /db_xref="PDB:3AVO" /db_xref="PDB:3AVP" /db_xref="PDB:3AVQ" /db_xref="PDB:4BFS" /db_xref="PDB:4BFT" /db_xref="PDB:4BFU" /db_xref="PDB:4BFV" /db_xref="PDB:4BFW" /db_xref="PDB:4BFX" /db_xref="PDB:4BFY" /db_xref="PDB:4BFZ" /db_xref="PDB:5XLV" /db_xref="PDB:5XLW" /db_xref="PDB:5XMB" /db_xref="UniProtKB/Swiss-Prot:P9WPA7" /inference="protein motif:PROSITE:PS00017" /experiment="EXISTENCE: identified in proteomics study" BEGIN 1 MSRLSEPSPY VEFDRRQWRA LRMSTPLALT EEELVGLRGL GEQIDLLEVE EVYLPLARLI 61 HLQVAARQRL FAATAEFLGE PQQNPDRPVP FIIGVAGSVA VGKSTTARVL QALLARWDHH 121 PRVDLVTTDG FLYPNAELQR RNLMHRKGFP ESYNRRALMR FVTSVKSGSD YACAPVYSHL 181 HYDIIPGAEQ VVRHPDILIL EGLNVLQTGP TLMVSDLFDF SLYVDARIED IEQWYVSRFL 241 AMRTTAFADP ESHFHHYAAF SDSQAVVAAR EIWRTINRPN LVENILPTRP RATLVLRKDA 301 DHSINRLRLR KL //