LOCUS       CCP43548.1               433 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable aminopeptidase
            PepC protein.
ACCESSION   AL123456-826
PROTEIN_ID  CCP43548.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="pepC"
                     /locus_tag="Rv0800"
                     /note="Rv0800, (MTCY07H7A.09c), len: 433 aa. Probable
                     pepC,aminopeptidase I, highly similar (but shorter 17 aa)
                     to Q50022|PEPX aminopeptidase from Mycobacterium leprae
                     (443 aa), FASTA scores: opt: 2237, E(): 0, (78.3% identity
                     in 433 aa overlap). Also highly similar to others from
                     Eukaryotes and bacteria, e.g. T36482 probable
                     aminopeptidase from Streptomyces coelicolor (432
                     aa),P14904|AMPL_YEAST vacuolar aminopeptidase I precursor
                     from Saccharomyces cerevisiae (514 aa), FASTA scores: opt:
                     425,E(): 4.8e-21, (31.0% identity in 445 aa overlap); etc.
                     Also similar to hypothetical proteins e.g.
                     P38821|YHR3_YEAST hypothetical 54.2 kDa protein from
                     Saccharomyces cerevisiae (490 aa), FASTA scores: opt: 429,
                     E(): 2.5e-21, (34.8% identity in 443 aa overlap); etc.
                     Conserved in M. tuberculosis, M. leprae, M. bovis and M.
                     avium paratuberculosis; predicted to be essential for in
                     vivo survival and pathogenicity (See Ribeiro-Guimaraes and
                     Pessolani, 2007)."
                     /db_xref="EnsemblGenomes-Gn:Rv0800"
                     /db_xref="EnsemblGenomes-Tr:CCP43548"
                     /db_xref="GOA:P9WHT1"
                     /db_xref="InterPro:IPR001948"
                     /db_xref="InterPro:IPR022984"
                     /db_xref="InterPro:IPR023358"
                     /db_xref="UniProtKB/Swiss-Prot:P9WHT1"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MAATAHGLCE FIDASPSPFH VCATVAGRLL GAGYRELREA DRWPDKPGRY FTVRAGSLVA
       61 WNAEQSGHTQ VPFRIVGAHT DSPNLRVKQH PDRLVAGWHV VALQPYGGVW LHSWLDRDLG
      121 ISGRLSVRDG TGVSHRLVLI DDPILRVPQL AIHLAEDRKS LTLDPQRHIN AVWGVGERVE
      181 SFVGYVAQRA GVAAADVLAA DLMTHDLTPS ALIGASVNGT ASLLSAPRLD NQASCYAGME
      241 ALLAVDVDSA SSGFVPVLAI FDHEEVGSAS GHGAQSDLLS SVLERIVLAA GGTREDFLRR
      301 LTTSMLASAD MAHATHPNYP DRHEPSHPIE VNAGPVLKVH PNLRYATDGR TAAAFALACQ
      361 RAGVPMQRYE HRADLPCGST IGPLAAARTG IPTVDVGAAQ LAMHSARELM GAHDVAAYSA
      421 ALQAFLSAEL SEA
//