LOCUS CCP42892.1 554 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) protein. ACCESSION AL123456-170 PROTEIN_ID CCP42892.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /gene="fadD5" /locus_tag="Rv0166" /note="Rv0166, (MTCI28.06), len: 554 aa. Probable fadD5,fatty-acid-CoA synthetase, similar to many eg LCFA_ECOLI|P29212 long-chain-fatty-acid--CoA ligase (561 aa), FASTA scores: opt: 612, E(): 0, (29.4% identity in 534 aa overlap). Also similar to many other fatty-acid-CoA ligases from Mycobacterium tuberculosis e.g. MTCY07A7.11c FASTA score: (35.3% identity in 487 aa overlap), MTV013_10,MTY25D10_30, etc. Contains PS00455 putative AMP-binding domain signature." /db_xref="EnsemblGenomes-Gn:Rv0166" /db_xref="EnsemblGenomes-Tr:CCP42892" /db_xref="GOA:O07411" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR042099" /db_xref="UniProtKB/TrEMBL:O07411" /inference="protein motif:PROSITE:PS00455" BEGIN 1 MTAQLASHLT RALTLAQQQP YLARRQNWVN QLERHAMMQP DAPALRFVGN TMTWADLRRR 61 VAALAGALSG RGVGFGDRVM ILMLNRTEFV ESVLAANMIG AIAVPLNFRL TPTEIAVLVE 121 DCVAHVMLTE AALAPVAIGV RNIQPLLSVI VVAGGSSQDS VFGYEDLLNE AGDVHEPVDI 181 PNDSPALIMY TSGTTGRPKG AVLTHANLTG QAMTALYTSG ANINSDVGFV GVPLFHIAGI 241 GNMLTGLLLG LPTVIYPLGA FDPGQLLDVL EAEKVTGIFL VPAQWQAVCT EQQARPRDLR 301 LRVLSWGAAP APDALLRQMS ATFPETQILA AFGQTEMSPV TCMLLGEDAI AKRGSVGRVI 361 PTVAARVVDQ NMNDVPVGEV GEIVYRAPTL MSCYWNNPEA TAEAFAGGWF HSGDLVRMDS 421 DGYVWVVDRK KDMIISGGEN IYCAELENVL ASHPDIAEVA VIGRADEKWG EVPIAVAAVT 481 NDDLRIEDLG EFLTDRLARY KHPKALEIVD ALPRNPAGKV LKTELRLRYG ACVNVERRSA 541 SAGFTERREN RQKL //