LOCUS CCD69410.1 771 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Kinase suppressor of Ras A protein. ACCESSION BX284606-1923 PROTEIN_ID CCD69410.1 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="ksr-1" /locus_tag="CELE_F13B9.5" /standard_name="F13B9.5" /note="Confirmed by transcript evidence" /db_xref="EnsemblGenomes-Gn:WBGene00002239" /db_xref="EnsemblGenomes-Tr:F13B9.5.1" /db_xref="EnsemblGenomes-Tr:F13B9.5.2" /db_xref="GOA:G5EFD2" /db_xref="InterPro:IPR000719" /db_xref="InterPro:IPR001245" /db_xref="InterPro:IPR002219" /db_xref="InterPro:IPR008266" /db_xref="InterPro:IPR011009" /db_xref="InterPro:IPR017441" /db_xref="UniProtKB/Swiss-Prot:G5EFD2" /db_xref="WormBase:WBGene00002239" intron_pos 36:1 (1/13) intron_pos 60:0 (2/13) intron_pos 119:0 (3/13) intron_pos 149:1 (4/13) intron_pos 198:1 (5/13) intron_pos 254:2 (6/13) intron_pos 290:0 (7/13) intron_pos 338:1 (8/13) intron_pos 462:0 (9/13) intron_pos 529:0 (10/13) intron_pos 632:2 (11/13) intron_pos 678:2 (12/13) intron_pos 722:0 (13/13) BEGIN 1 MMQTQVASRA GYSNLPQFGA GIAQDIKTQA INNLKECLKL TTINRFLTSS YEEDAKSVER 61 KIFSAVYQMT KIGLIDREKR EINAIWFTFV GLSAQNIRHL EICSITDFNA LFSITNQELR 121 SLADRGRLDV ETKRKLLQST VILQNHWNAY HSRTSSGSTD EPSGQSTPAI VTPSPKFNVP 181 SLSVTSAKMI QSSSMGFATT PKSPKTSSRL VHAIPHKWHR STKFRFSGDA VCHFCQRPLG 241 FGFLNAWEKC RSCKWKVHTQ CKGRVGDSCG LTPDHLRFLF DKLIQENNGG MWKDPQSVPG 301 SRSMNEPAFQ FPDTAIDSSS STNSSAPSTP ALPAGISGNV SSLTAPYRSE RKFLFPDTEN 361 YSVHNRLPIL VISEGDHPTT TEIQQETENH NKSAAASMSG NIESEGTIVA NHEDSTGSQE 421 VDSEAAPSQE AVDKFNKRAD GGFTWERHAW NMSTIRGPNA QASWNEVTIQ FETIEFDKQA 481 PIIGRGRFGK VLRGFHYGDV AVKVYTMEHI SDASKKAEEF KLEVSAYKNT RHDNIALFLG 541 YFMSDGQYGM VMSLSKGSQS LYTLLHVVRE KLDLATTRKI AQQICQAVSY LHTKKILHKD 601 LRSKNILLES KNKVVITDFG ILSMKRLAHP KQKSGYLTSK FWTNYIAPEL AMAMRTEYDE 661 YECDDFPFSE NSDVYAFGCV WFEMLTGALP YAGELPHQIL FAKTQGIRPV LPNVKCTQEL 721 KELLVSCWNT APQDRPTLTD INLKLTALPK KPRVNRSPSF PVMMKSYEST F //