LOCUS CCD63279.2 683 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Suppressor of presenilin protein 3 protein. ACCESSION BX284606-998 PROTEIN_ID CCD63279.2 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="spr-3" /locus_tag="CELE_C07A12.5" /standard_name="C07A12.5b" /note="Confirmed by transcript evidence" /db_xref="EnsemblGenomes-Tr:C07A12.5a" /db_xref="WormBase:WBGene00005008" intron_pos 18:0 (1/4) intron_pos 225:2 (2/4) intron_pos 322:0 (3/4) intron_pos 587:1 (4/4) BEGIN 1 MPPRKRKLEE LKNEQGEGSY KCHLCGQCFY RGCGLASHLR RHAPVTFDCE HCAYTCKHKY 61 AYDRHLLQSH PELVESGPLV RMFKNEDEDA PMPILEREAD VSDDAVKYEA LSSFSEPEPI 121 SYKCPLCIST FGSHARAVYH ILSHRVKLYQ APKSLKFFSR KTMQALGGFR LESQLMIKWR 181 LQYDNRSVDE KRTRLWRYME ENFGHEHLKQ PKLESDNPST SSSFESQTNL NDSSIIKKKL 241 VMKCGTVFGQ RLIHDNTQYY LCRNCPYVSW NVSSLWRHFR HHIQKSKQSW TCIACSYSSS 301 SRVKIDLHVK MHKEMPEIDL EFATWLRYER RINKNDLNKP TNKKKKPDGG NGSNHSDMRS 361 LHAFLSLKNS KNNVVKHDID APTLHPLSPA PKLVAMTQFD FGEIVTYKSV NPLHQINKNN 421 SNPTVLPNKR NSIKTSKSDT QIALSVKQSS SMKMVKVSPG KVYQLPKTSK FYRPESPDSL 481 ASNNSAHGDE IESTSSDQFQ QSVKVPKYED FLNMKPVMPY FQKQRHPLEA IAMYEKAKRE 541 YEKNHCFPNL PIFEFNIEYK NLHPLAKAQY GKNNMKEYFL NEMEVEKSRE CTDCPFKHND 601 LQQFRLHRDK HFYGGSHTCP ECNYSSNNHN QVVEHTFVDH YLSDVRLVEG LPSSDSEDDN 661 IPVPPDTPQR KKKAPKRGKR RGW //