LOCUS CAD36489.1 611 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Sodium/hydrogen exchanger protein. ACCESSION BX284606-2505 PROTEIN_ID CAD36489.1 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="nhx-5" /locus_tag="CELE_F57C7.2" /standard_name="F57C7.2b" /note="Confirmed by transcript evidence" /db_xref="EnsemblGenomes-Gn:WBGene00003733" /db_xref="EnsemblGenomes-Tr:F57C7.2b" /db_xref="GOA:G5ECW8" /db_xref="InterPro:IPR002090" /db_xref="InterPro:IPR004709" /db_xref="InterPro:IPR006153" /db_xref="InterPro:IPR018422" /db_xref="UniProtKB/TrEMBL:G5ECW8" /db_xref="WormBase:WBGene00003733" intron_pos 34:0 (1/16) intron_pos 81:1 (2/16) intron_pos 119:2 (3/16) intron_pos 156:0 (4/16) intron_pos 207:2 (5/16) intron_pos 239:1 (6/16) intron_pos 274:2 (7/16) intron_pos 304:1 (8/16) intron_pos 354:1 (9/16) intron_pos 387:0 (10/16) intron_pos 422:0 (11/16) intron_pos 450:2 (12/16) intron_pos 480:0 (13/16) intron_pos 510:2 (14/16) intron_pos 567:2 (15/16) intron_pos 603:0 (16/16) BEGIN 1 MKLLWTISTI LLISSTVAGS NNGNTRLDMA AQRRASNIHR MDTIILLTYV SVMVLIVVTA 61 WAFKHYRFRF IHESGVTLFY GLLIGFVIRY FGLGLLQSQT FDVITKNKTI VKEPPDYLML 121 EVKPEGGSRV SFHYELIEGF FADKRKKIEQ QIEQKSVFSP EVFFNMLIPP IIFNAGYSLK 181 KRHFFRNIGS ILAIVFIGTT ISCFGTGCLM FVFTSIFQMG YSFKELLFFG ALISATDPVT 241 IISVFNDMNV EADLFALIFG ESALNDAVAI VLSEVIENFS TSSEAITLQD FGSAIAGFAG 301 VFFGSLMLGF MIGCMNAFLT KMTLISEHAL LESSLFVLIS YISFLVAEVC GLTGIVSVLF 361 CGIAQAHYTY NNLSDESQSN TKHFFHMVSF IMESFIFCYI GVSVFVTNNQ RWSFSFLLFS 421 LISITASRAL FVYPLSWLLN IRRRPKIPKR YQHMILFAGL RGAMAFALAG RNTSTENRQM 481 IFATTTAVVI VTVLVNGGLT SWMIDYLQIK HGKDAIEEGQ RLENSMSSSP ADQHSDLDES 541 VPVTMSPGLN PWDKAFLPRK WYHFDASFMK PLLTHATPSL EQTLPPFCLP LTSLLTSSRQ 601 RAGETSSFDC E //