LOCUS       CAC06612.1               199 aa    PRT              HUM 07-OCT-2008
DEFINITION  Homo sapiens inducible T-cell co-stimulator protein.
ACCESSION   AJ277832-1
PROTEIN_ID  CAC06612.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2641)
  AUTHORS   Hutloff A.
  JOURNAL   Submitted (05-MAY-2000) to the INSDC. Hutloff A., Molecular
            Immunology, Robert Koch-Institut, Nordufer 20, Berlin, 13353,
            GERMANY.
REFERENCE   2
  AUTHORS   Hutloff A., Dittrich A.M., Beier K.C., Eljaschewitsch B., Kraft R.,
            Anagnostopoulos I., Kroczek R.A.
  TITLE     ICOS is an inducible T-cell co-stimulator structurally and
            functionally related to CD28
  JOURNAL   Nature 397(6716), 263-266(1999).
   PUBMED   9930702
REFERENCE   3
  AUTHORS   Beier K.C., Hutloff A., Dittrich A.M., Heuck C., Rauch A.,
            Buechner K., Ludewig B., Ochs H.D., Mages H.W., Kroczek R.A.
  TITLE     Induction, binding specificity and function of human ICOS
  JOURNAL   Eur. J. Immunol. 30(12), 3707-3717(2000).
   PUBMED   11169414
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000246404"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /cell_line="MOLT-4V"
                     /cell_type="T-cell"
                     /db_xref="taxon:9606"
     protein         /gene="ICOS"
                     /function="immune response"
                     /db_xref="GOA:Q9Y6W8"
                     /db_xref="H-InvDB:HIT000246404.14"
                     /db_xref="HGNC:HGNC:5351"
                     /db_xref="InterPro:IPR013106"
                     /db_xref="InterPro:IPR013783"
                     /db_xref="InterPro:IPR039943"
                     /db_xref="UniProtKB/Swiss-Prot:Q9Y6W8"
                     /citation=[2]
BEGIN
        1 MKSGLWYFFL FCLRIKVLTG EINGSANYEM FIFHNGGVQI LCKYPDIVQQ FKMQLLKGGQ
       61 ILCDLTKTKG SGNTVSIKSL KFCHSQLSNN SVSFFLYNLD HSHANYYFCN LSIFDPPPFK
      121 VTLTGGYLHI YESQLCCQLK FWLPIGCAAF VVVCILGCIL ICWLTKKKYS SSVHDPNGEY
      181 MFMRAVNTAK KSRLTDVTL
//