LOCUS       CAB56222.1              1952 aa    PRT              HUM 07-OCT-2008
DEFINITION  Homo sapiens plexin-B1/SEP receptor protein.
ACCESSION   AJ011415-1
PROTEIN_ID  CAB56222.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5859)
  AUTHORS   Tamagnone L.
  JOURNAL   Submitted (18-SEP-1998) to the INSDC. Tamagnone L., Molecular
            Oncology, Institute for Cancer Research, University of Torino, SP
            142, Candiolo, Torino, 10060, ITALY.
REFERENCE   2
  AUTHORS   Tamagnone L., Artigiani S., Longati P., Comoglio P.M.
  TITLE     The SEX/plexin receptor family
  JOURNAL   Unpublished.
REFERENCE   3
  AUTHORS   Tamagnone L., Artigiani S., Chen H., He Z., Ming G.L., Song H.L.,
            Chedotal A., Winberg M.L., Goodman C.S., Poo M.M.,
            Tessier-Lavigne M., Comoglio P.M.
  TITLE     Plexins are a large family of receptors for transmembrane,
            secreted, and GPI-anchored semaphorins in vertebrates
  JOURNAL   Cell 99(1), 71-80(1999).
   PUBMED   10520995
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000244511"
                     /organism="Homo sapiens"
                     /chromosome="3"
                     /mol_type="mRNA"
                     /cell_line="GTL-16"
                     /cell_type="gastric carcinoma"
                     /db_xref="taxon:9606"
     protein         /gene="plexin-B1/SEP"
                     /function="plasma membrane receptor"
                     /note="splice variant R"
                     /note="extracellular domain sligthly shorter than
                     canonical Sep and acquires an RGD motif at splice
                     junction"
                     /db_xref="GOA:O43157"
                     /db_xref="H-InvDB:HIT000244511.13"
                     /db_xref="HGNC:HGNC:9103"
                     /db_xref="InterPro:IPR001627"
                     /db_xref="InterPro:IPR002165"
                     /db_xref="InterPro:IPR002909"
                     /db_xref="InterPro:IPR008936"
                     /db_xref="InterPro:IPR013548"
                     /db_xref="InterPro:IPR013783"
                     /db_xref="InterPro:IPR014756"
                     /db_xref="InterPro:IPR015943"
                     /db_xref="InterPro:IPR016201"
                     /db_xref="InterPro:IPR031148"
                     /db_xref="InterPro:IPR036352"
                     /db_xref="InterPro:IPR041019"
                     /db_xref="InterPro:IPR041362"
                     /db_xref="PDB:2JPH"
                     /db_xref="PDB:2OS6"
                     /db_xref="PDB:2R2O"
                     /db_xref="PDB:2REX"
                     /db_xref="PDB:3HM6"
                     /db_xref="PDB:3OL2"
                     /db_xref="PDB:3SU8"
                     /db_xref="PDB:3SUA"
                     /db_xref="PDB:5B4W"
                     /db_xref="UniProtKB/Swiss-Prot:O43157"
BEGIN
        1 MPALGPALLQ ALWAGWVLTL QPLPPTAFTP NGTYLQHLAR DPTSGTLYLG ATNFLFQLSP
       61 GLQLEATVST GPVLDSRDCL PPVMPDECPQ AQPTNNPNQL LLVSPGALVV CGSVHQGVCE
      121 QRRLGQLEQL LLRPERPGDT QYVAANDPAV STVGLVAQGL AGEPLLFVGR GYTSRGVGGG
      181 IPPITTRALW PPDPQAAFSY EETAKLAVGR LSEYSHHFVS AFARGASAYF LFLRRDLQAQ
      241 SRAFRAYVSR VCLRDQHYYS YVELPLACEG GRYGLIQAAA VATSREVAHG EVLFAAFSSA
      301 APPTVGRPPS AAAGASGASA LCAFPLDEVD RLANRTRDAC YTREGRAEDG TEVAYIEYDV
      361 NSDCAQLPVD TLDAYPCGSD HTPSPMASRV PLEATPILEW PGIQLTAVAV TMEDGHTIAF
      421 LGDSQGQLHR VYLGPGSDGH PYSTQSIQQG SAVSRDLTFD GTFEHLYVMT QSTLLKVPVA
      481 SCAQHLDCAS CLAHRDPYCG WCVLLGRCSR RSECSRGQGP EQWLWSFQPE LGCLQVAAMS
      541 PANISREETR EVFLSVPDLP PLWPGESYSC HFGEHQSPAL LTGSGVMCPS PDPSEAPVLP
      601 RGADYVSVSV ELRFGAVVIA KTSLSFYDCV AVTELRPSAQ CQACVSSRWG CNWCVWQHLC
      661 THKASCDAGP MVASHQSPLV SPDPPARGDG DSAELEGPPA PLILPSSLDY QYDTPGLWEL
      721 EEATLGASSC PCVESVQGST LMPVHVEREI RLLGRNLHLF QDGPGDNECV MELEGLEVVV
      781 EARVECEPPP DTQCHVTCQQ HQLSYEALQP ELRVGLFLRR AGRLRVDSAE GLHVVLYDCS
      841 VGHGDCSRCQ TAMPQYGCVW CEGERPRCVT REACGEAEAV ATQCPAPLIH SVEPLTGPVD
      901 GGTRVTIRGS NLGQHVQDVL GMVTVAGVPC AVDAQEYEVS SSLVCITGAS GEEVAGATAV
      961 EVPGRGRGVS EHDFAYQDPK VHSIFPARGP RAGGTRLTLN GSKLLTGRLE DIRVVVGDQP
     1021 CHLLPEQQSE QLRCETSPRP TPATLPVAVW FGATERRLQR GQFKYTLDPN ITSAGPTKSF
     1081 LSGGREICVR GQNLDVVQTP RIRVTVVSRM LQPSQGLGRR RRVVPETACS LGPSCSSQQF
     1141 EEPCHVNSSQ LITCRTPALP GLPEDPWVRV EFILDNLVFD FATLNPTPFS YEADPTLQPL
     1201 NPEDPTMPFR HKPGSVFSVE GENLDLAMSK EEVVAMIGDG PCVVKTLTRH HLYCEPPVEQ
     1261 PLPRHHALRE APDSLPEFTV QMGNLRFSLG HVQYDGESPG AFPVAAQVGL GVGTSLLALG
     1321 VIIIVLMYRR KSKQALRDYK KVQIQLENLE SSVRDRCKKE FTDLMTEMTD LTSDLLGSGI
     1381 PFLDYKVYAE RIFFPGHRES PLHRDLGVPE SRRPTVEQGL GQLSNLLNSK LFLTKFIHTL
     1441 ESQRTFSARD RAYVASLLTV ALHGKLEYFT DILRTLLSDL VAQYVAKNPK LMLRRTETVV
     1501 EKLLTNWMSI CLYTFVRDSV GEPLYMLFRG IKHQVDKGPV DSVTGKAKYT LNDNRLLRED
     1561 VEYRPLTLNA LLAVGPGAGE AQGVPVKVLD CDTISQAKEK MLDQLYKGVP LTQRPDPRTL
     1621 DVEWRSGVAG HLILSDEDVT SEVQGLWRRL NTLQHYKVPD GATVALVPCL TKHVLRENQD
     1681 YVPGERTPML EDVDEGGIRP WHLVKPSDEP EPPRPRRGSL RGGERERAKA IPEIYLTRLL
     1741 SMKGTLQKFV DDLFQVILST SRPVPLAVKY FFDLLDEQAQ QHGISDQDTI HIWKTNSLPL
     1801 RFWINIIKNP QFVFDVQTSD NMDAVLLVIA QTFMDACTLA DHKLGRDSPI NKLLYARDIP
     1861 RYKRMVERYY ADIRQTVPAS DQEMNSVLAE LSWNYSGDLG ARVALHELYK YINKYYDQII
     1921 TALEEDGTAQ KMQLGYRLQQ IAAAVENKVT DL
//