LOCUS       CAB5248089.1             321 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LYSR-FAMILY)
            protein.
ACCESSION   LT708304-388
PROTEIN_ID  CAB5248089.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0384"
                     /note="Mb0384, -, len: 321 aa. Equivalent to Rv0377, len:
                     321 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 321 aa overlap). Probable transcription
                     regulator, lysR family, showing similarity with many
                     hypothetical transcriptional regulators lysR homolog e.g.
                     P32484|YEIE_ECOLI|M89774 HYPOTHETICAL TRANSCRIPTIONAL
                     REGULATOR from Escherichia coli (293 aa), FASTA scores:
                     opt: 265, E(): 4.9e-11, (28.6% identity in 266 aa
                     overlap). Also similar to Rv2282c from Mycobacterium
                     tuberculosis. Contains PS00044 bacterial regulatory
                     protein lysR family signature. SEEMS TO BELONG TO THE LYSR
                     FAMILY OF TRANSCRIPTIONAL REGULATORS. Mb0384 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MTPAQLRAYS AVVRLGSVRA AAAELGLSDA GVSMHVAALR KELDDPLFTR TGAGLAFTPG
       61 GLRLASRAVE ILGLQQQTAI EVTEAAHGRR LLRIAASSAF AEHAAPGLIE LFSSRADDLS
      121 VELSVHPTSR FRELICSRAV DIAIGPASES SIGSDGSIFL RPFLKYQIIT VVAPNSPLAA
      181 GIPMPALLRH QQWMLGPSAG SVDGEIATML RGLAIPESQQ RIFQSDAAAL EEVMRVGGAT
      241 LAIGFAVAKD LAAGRLVHVT GPGLDRAGEW CVATLAPSAR QPAVSELVGF ISTPRCIQAM
      301 IRGSGVGVTR FRPKVHVTLW S
//