LOCUS       CAB5248017.1             302 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            DEHYDROGENASE/REDUCTASE protein.
ACCESSION   LT708304-316
PROTEIN_ID  CAB5248017.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0311"
                     /note="Mb0311, -, len: 302 aa. Equivalent to Rv0303, len:
                     302 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 302 aa overlap). Possible
                     dehydrogenase/reductase (EC 1.-.-.-), similar to various
                     NADPH dehydrogenases and other NADPH oxidoreductases e.g.
                     O48741|PORC_ARATH|7488284|T00897 PROTOCHLOROPHYLLIDE
                     REDUCTASE C CHLOROPLAST PRECURSOR (EC 1.3.1.33)
                     (NADPH-PROTOCHLOROPHYLLIDE OXIDOREDUCTASE C) from
                     Arabidopsis thaliana (401 aa); Q42850 NADPH DEHYDROGENASE
                     (EC 1.6.99. 1) (395 aa), FASTA scores: opt: 347, E():
                     3.8e-16, (35.4% identity in 319 aa overlap). Protein
                     product from Mb0311 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0311 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MNTGTAVITG ASSGLGLQCA RALLRRDASW HVVLAVRDPA RGRAAMEELG EPNRCSVLEV
       61 DLASVRSVRS FVETVRTTPL PPIRALVCNA GLQVVSGIAF TDDGVEMTFG VNHLGHFALV
      121 TGILDWLARP ARIVVVSSGT HDPSKHTGMP DPRYTCAADL AHPPTDQNTP AEGRRRYTTS
      181 KLCNVLFTYE LDRRLDHGEQ GVMVNAFDPG LMPGSGLARD YPPILRLAYR LLSPMLRVLP
      241 FVHSTRVSGE HLAALAVDPR FAGVTGQYFA GAKAIRSSAE SYDRAKALDL WETSERLLAQ
      301 VT
//