LOCUS       CAB5248006.1             331 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 esx
            conserved component ecce3. esx-3 type vii secretion system
            protein. probable transmembrane protein. protein.
ACCESSION   LT708304-305
PROTEIN_ID  CAB5248006.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="ecce3"
                     /locus_tag="BQ2027_MB0300"
                     /note="Mb0300, -, len: 331 aa. Equivalent to Rv0292, len:
                     331 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 331 aa overlap). Probable conserved
                     transmembrane protein (has two hydrophobic segments at
                     N-terminal end), equivalent to CAC32058.1|AL583926
                     conserved membrane protein from Mycobacterium leprae (339
                     aa). Protein product from Mb0300 detected using shotgun
                     mass spectrometry and SWATH mass spectrometry. Mb0300
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MNPIPSWPGR GRVTLVLLAV VPVALAYPWQ STRDYVLLGV AAAVVIGLFG FWRGLYFTTI
       61 ARRGLAILRR RRRIAEPATC TRTTVLVWVG PPASDTNVLP LTLIARYLDR YGIRADTIRI
      121 TSRVTASGDC RTWVGLTVVA DDNLAALQAR SARIPLQETA QVAARRLADH LREIGWEAGT
      181 AAPDEIPALV AADSRETWRG MRHTDSDYVA AYRVSADAEL PDTLPAIRSR PAQETWIALE
      241 IAYAAGSSTR YTVAAACALR TDWRPGGTAP VAGLLPQHGN HVPALTALDP RSTRRLDGHT
      301 DAPADLLTRL HWPTPTAGAH RAPLTNAVSR T
//