LOCUS       CAB5247986.1             193 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Glyoxalase
            family protein protein.
ACCESSION   LT708304-285
PROTEIN_ID  CAB5247986.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0280"
                     /note="Mb0280, -, len: 193 aa. Equivalent to Rv0274, len:
                     193 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 193 aa overlap). Conserved
                     hypothetical protein, highly similar to
                     AAK25058.1|AE005973 conserved hypothetical protein from
                     Caulobacter crescentus (174 aa). Shows also some
                     similarity to others hypothetical proteins e.g.
                     AJ002571|BSAJ2571_7 from Bacillus subtilis (316 aa), FASTA
                     scores: opt: 138, E(): 0.033, (27.1% identity in 133 aa
                     overlap). Previous hits with Q56415|M85195
                     FOSFOMYCIN-RESISTANCE PROTEIN from SERRATIA MARCESCENS
                     (141 aa), FASTA scores: opt: 82, E(): 1.1e -08, (29.1%
                     identity in 151 aa overlap). Contains PS00082 Extradiol
                     ring-cleavage dioxygenases signature near C-terminus.
                     TBparse score is 0.914. Protein product from Mb0280
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb0280 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MIKPHNTNTE FELGGINHVA LVCSDMARTV DFYSNILGMP LIKALDLPGG QGQHFFFDAG
       61 NGDCVAFFWF ADAPDRVPGL SSPVAIPGIG DITSAVSTMN HLAFHVPAER FDAYRQRLKD
      121 KGVRVGPVLN HDDSETQVSA VVHPGVYVRS FYFQDPDGIT LEFACWTKEF TTSDAQAVPK
      181 TAADRRPPVA ADR
//