LOCUS       CAB5247958.1             436 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED INTEGRAL MEMBRANE PROTEIN protein.
ACCESSION   LT708304-257
PROTEIN_ID  CAB5247958.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0252"
                     /note="Mb0252, -, len: 436 aa. Equivalent to Rv0246, len:
                     436 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 436 aa overlap). Probable conserved
                     integral membrane protein, similar to
                     Rv2209|1237062|CAA94252.1|Z70283|Q10398|YM09_MYCTU from
                     Mycobacterium tuberculosis (512 aa), FASTA scores: opt:
                     712, E(): 0, (33.2% identity in 422 aa overlap). Mb0252
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
BEGIN
        1 MAKTSHRVSS ADGMSKRILR LIIAQSGFYS AALQLGNVSI VLPFVVAELD AELWIAALIF
       61 PAFTAGGAIG NVVAPPAVAA VPRRHRLFII VSCLAVLAGV NALCATIGKG SVAGILLVVN
      121 VTLIGVVSVI SFVAFADLVA AMPSGTARAR ILLTEVGVGA ALTAVVAATL SFVPDQHPLS
      181 RNIHLLWTAA VAMAISAAIC RALPHRIVPR VHAAPGLHKL VYVGWTAIRT NGWYRRYLLV
      241 QVLFGSVVLG SSFHSIRVAA VPGDQPDEVV AVVLFVCVGL LGGIALWNRV RERFGLVGLF
      301 VGSALVSIAA AVLSIAFDLA GAWPNVVAIG LVIALVSIAN QSVFTAGQLW IARDAEPGLR
      361 TSLISFGQLV INAGLVGMGL ALGLIAQDHD AVWPVMIVLL LNLTAAYSAT RFAPAKSVDV
      421 RGLPQVSRTS RPKTGG
//