LOCUS       CAB5247942.1             568 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ACYL-COA DEHYDROGENASE FADE4 protein.
ACCESSION   LT708304-241
PROTEIN_ID  CAB5247942.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fadE4"
                     /locus_tag="BQ2027_MB0236"
                     /note="Mb0236, fadE4, len: 568 aa. Equivalent to Rv0231,
                     len: 568 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 568 aa overlap). Probable fadE4,
                     acyl-CoA dehydrogenase (EC 1.3.99.-), similar to many e.g.
                     O29752 ACYL-COA DEHYDROGENASE (ACD-3) from Archaeoglobus
                     fulgidus (576 aa), FASTA scores: opt: 1788, E(): 0, (51.0%
                     identity in 577 aa overlap); ACDB_BACSU|P45857 acyl-coa
                     dehydrogenase from Bacillus subtilis (379 aa), FASTA
                     scores: opt: 232, E(): 2.2e- 08, (21.6% identity in 291 aa
                     overlap). Protein product from Mb0236 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb0236 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
BEGIN
        1 MLLNPNHLTR KYPDRRSGEI MAATVDFFES RGKARLKHDD HERIWYSDFL DFVGRERIFA
       61 SLLTPASYGA DDCRWDTYRI SEFAEIMGFY GLSYWYPFQV TALGLGPIWM SANEDAKRKA
      121 AAGLEAGEVF AFGLSEQTHG ADVYQTDMIL TPSDGGWTAN GEKYYIGNAN VARMVSTFGK
      181 IAGTPESQEY VFFVADSQHE RYDLIKNVVN SQNYVANYAL RDYPVTEADI LHRGAEAFHA
      241 ALNTVNVCKY NLGWGAIGMC THALYESVTH AANRHLYGTV VTDFSHVRRL LTDAYVRLIA
      301 MKLVASRASD YMRSASAADR RYLLYSPLTK AKVTSEGERV ITALWDVIAA KGVEKDTFFE
      361 TVAREIGLLP RLEGTVHINI GLLGKFMPNY LFAPDSTLPV IPRRDDAADD AFLFAQGPTG
      421 GLGKVRFHDW RASFDTCAHL PNVALLREQV DVFAELLASA TPDAAQQKDI DFAFGVGQLF
      481 ANVPYAQLIL EEARLSGVDE ALIDEIFGVL VRDFNTHAVE LHGRSATTAE QARFAMRMVR
      541 RPVHDPARYD QIWKDHVLAL NGAYQMAP
//