LOCUS       CAB5247940.1             226 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            conserved membrane protein with pin domain protein.
ACCESSION   LT708304-239
PROTEIN_ID  CAB5247940.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0234C"
                     /note="Mb0234c, -, len: 226 aa. Equivalent to Rv0229c,
                     len: 226 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 226 aa overlap). Possible conserved
                     membrane protein, similar to several proteins from
                     Mycobacterium tuberculosis. Other possible start sites and
                     could be shorter as C-terminal region has some similarity
                     with Rv2757c|D70880 from Mycobacterium tuberculosis (138
                     aa), FASTA scores: E(): 1e-15, (45.3% identity in 137 aa
                     overlap), and Rv0301, Rv2546, etc. Also some similarity
                     with Q48177 virulence associated protein C (132 aa), FASTA
                     scores: opt: 101, E(): 0.6, (24.3% identity in 136 aa
                     overlap). Contains PS00626 Regulator of chromosome
                     condensation (RCC1) signature 2. Protein product from
                     Mb0234c detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb0234c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MRQPRRANAM GLALCIYIGS LLIYTPIHGE TSRRHRRAGF KHGSYRIGHD DDQRHRQRGP
       61 AASHVSASST RRRRSRHAGR RTARGPRRSM ALKYLLDTSV IKRLSRPAVR RAVEPLAEAG
      121 AVARTQITDL EVGYSARNET EWQRLMVALS AFDLIESTAS HHRRALGIQR LLAARSQRGR
      181 KIPDLLIAAA GEEHGLVVLH YDADFDLIAA VTGQPCQWIV PAGTID
//