LOCUS       CAB5247909.1             748 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            OXIDOREDUCTASE protein.
ACCESSION   LT708304-208
PROTEIN_ID  CAB5247909.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0203"
                     /note="Mb0203, -, len: 748 aa. Equivalent to Rv0197, len:
                     762 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.9% identity in 748 aa overlap). Possible
                     oxidoreductase (EC 1.-.-.-), similar to others e.g.
                     9948789|AAG06102.1|AE004699_7|B83307 probable
                     molybdopterin oxidoreductase from Pseudomonas aeruginosa
                     strain PAO1 (769 aa); 5441785|CAB46809.1|AL096811|T36812
                     probable dehydrogenase from Streptomyces coelicolor (747
                     aa), FASTA scores: opt: 617, E(): 9.8e-30, (29.9% identity
                     in 762 aa overlap); BAB04334.1|AP001509 assimilatory
                     nitrate reductase (catalytic subunit) from Bacillus
                     halodurans (743 aa); etc. REMARK-M.bovis-M.tuberculosis:
                     In Mycobacterium bovis, a single base transversion (t-g)
                     introduces a stop codon that leads to a shorter product
                     compared to its homolog in Mycobacterium tuberculosis
                     strain H37Rv (748 aa versus 762 aa)."
BEGIN
        1 MTSSDWLPTA CILCECNCGI VVQVDDRRLA RIRGDKAHPG SAGYTCNKAL RLDHYQNNRA
       61 RLSSPMRRRA DGTYEEIDWD TAIVEIAEGF KQIRDTHGGD KIFYYGGGGQ GNHLGGAYSG
      121 AFLKALGSRY RSNALAQEKT GEAWVDFQLY GGHTRGEFEN AEVSVFVGKN PWMSQSFPRA
      181 RVVLNEIAKD PGRSMIVIDP VVTDTAKMAD FHLRVQPGCD AWCLAALAAV LVQENLCNEA
      241 FLAAHVHGVD TVRAALQEVP VADYAQRCGV DEELLRAAAR RIGTAASVSV FEDLGIQQAP
      301 NSTVCSYLNK LLWILTGNFA KKGGQHLHSS FAPLFSQVSG RTPVTGAPII AGLIPGNVVP
      361 EEILTEHPDR FRAMIVESGN PAHSLADSAA CRAAFQALEL MVVVDVAMTE TARLAHYVLP
      421 AASQFEKPEA TFFNFEFPRN GFQLRRPLFP PLPGTLPEPE IWARLVRALG VVDEADLRPL
      481 REAAAQGRQA YTEAFLAAAA TNPTVAKLTA YVLYETLGPT LPDGLAGAAA LWGLAQKTAM
      541 AYPDAVRRAG HADGNALFDA ILERPSGVTF TVHNYEDDFA LISHPDHKIA LEIPEMLAEI
      601 RSLTQTPSRL TTPQLPIVLS VGERRAYTAN DIFRDPSWRK RDANGALRVS VEDAQALGLA
      661 DGCLARITTA AGSAEATVEV TETMLAGHAA LPNGFGLDYT GDDGRTVVAG VAPNALTSTR
      721 WRDPYAGTPW HKHVPAAIRR ADAESPIW
//