LOCUS       CAB5247865.1             366 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            NAD(P) TRANSHYDROGENASE (SUBUNIT ALPHA) PNTAa [FIRST PART;
            CATALYTIC PART] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE
            SUBUNIT ALPHA) (NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE
            SUBUNIT ALPHA) protein.
ACCESSION   LT708304-164
PROTEIN_ID  CAB5247865.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="pntAa"
                     /locus_tag="BQ2027_MB0160"
                     /standard_name="pntAA"
                     /note="Mb0160, pntAa, len: 366 aa. Equivalent to Rv0155,
                     len: 366 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 366 aa overlap). Probable pntAa, first
                     part of NAD(P) transhydrogenase subunit alpha (EC
                     1.6.1.2), similar to N-terminus of others e.g.
                     PNTA_ECOLI|P07001|P76888|B1603 NAD (P) transhydrogenase
                     subunit alpha from Escherichia coli strain K12 (510 aa),
                     FASTA scores: opt: 921, E(): 0, (42.1% identity in 361 aa
                     overlap); PROTON-TRANSLOCATING NICOTINAMIDE NUCLEOTIDE
                     TRANSHYDROGENASE SUBUNIT PNTAA (EC 1.6.1.1). Protein
                     product from Mb0160 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0160 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTDPQTQSTR VGVVAESGPD ERRVALVPKA VASLVNRGVA VVVEAGAGER ALLPDELYTA
       61 VGASIGDAWA ADVVVKVAPP TAAEVGRLRG GQTLIGFLAP RNADNSIGAL TQAGVQAFAL
      121 EAIPRISRAQ VMDALSSQAN VSGYKAVLLA ASESTRFFPM LTTAAGTVKP ATVLVLGVGV
      181 AGLQALATAK RLGARTTGYD VRPEVADQVR SVGAQWLDLG ISASGEGGYA RELTDDERAQ
      241 QQKALEEAIS GFDVVITTAL VPGRPAPTLV TAAAVEAMKP GSVVVDLAGE TGGNCELTEP
      301 GRTVVKHDVT IAAPLNLPAT MPEHASELYS KNITALLDLL IKDGRLAPDF DDEVIAQSCV
      361 TRGKDS
//