LOCUS       CAB5247861.1             588 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 pe
            family protein pe1 protein.
ACCESSION   LT708304-160
PROTEIN_ID  CAB5247861.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PE1"
                     /locus_tag="BQ2027_MB0156C"
                     /note="Mb0156c, PE1, len: 588 aa. Equivalent to Rv0151c,
                     len: 588 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 588 aa overlap). Member of the
                     Mycobacterium tuberculosis PE family, with N-terminal
                     region similar to others e.g. MTV032_2 PE_PGRS family from
                     Mycobacterium tuberculosis (468 aa), FASTA scores: opt:
                     1125, E(): 0, (46.3% identity in 456 aa overlap);
                     MTCY493_24 from M. tuberculosis FASTA score: (42.5%
                     identity in 558 aa overlap). Also similar to upstream ORF
                     MTCI5.26c FASTA score: (54.7% identity in 464 aa overlap).
                     Also shows similarity to C-terminal part of some PPE
                     family proteins e.g. MTV049_21 from Mycobacterium
                     tuberculosis FASTA score: (41.5% identity in 591 aa
                     overlap). Mb0156c found to be expressed during exponential
                     growth in Sauton's minimal media by RNA-sequencing."
BEGIN
        1 MAPFGFTPKA RHNRGVALRS TYRLDRWVMG PVDKEGWGLS YVFAQPSVLA AAATDLAGIG
       61 SAINQATAAV AAPTTGLAAA AADEVSTALA TLFGAYGQQF QAISAQVAAF HNEFTQRLAA
      121 AANAFVNAEA TNTSALVQEA TAGLFKPTSP PVLPPMFNQN TAIIMGGTGS PIPTPSYVNA
      181 ITTLFIDPVV SNPVVKALVT PEELYPITGV KSLPFQTSVQ LGLQILDGAI WEQINAGNHV
      241 TVFGYSQSAV IASLEMQHLI SLGPNAPSPS QLNFILIGNE MNPNGGILAR IPGLNVTTLG
      301 LPFYGATPDN PYPTTTYTLE YDGFADFPRY PLNVLSDINA VFGILTVHTT YADLTPAQIA
      361 SATQLPTQGT TSNTYYIIET EHLPLLAPLR AIPVIGPPLA ALVEPNLEVI VNLGYGDPRF
      421 GYSTSPANVP TPFGLFPDVP ASVVADALVA GTQQGVNDFM VELPAALNTL PQTPMPAFPP
      481 YVPTLLPPPP PPQPATLINI ADTFASVVST GYSILLPTAD LGLAFVTILP AYDLTLFVNQ
      541 LAAGNLRAAI ELPLAATIGL AALGGMIEFI AIVVTLADIT QQLQSFSI
//