LOCUS       CAB5247838.1             447 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ACYL-CoA DEHYDROGENASE FADE1 protein.
ACCESSION   LT708304-137
PROTEIN_ID  CAB5247838.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fadE1"
                     /locus_tag="BQ2027_MB0136C"
                     /note="Mb0136c, fadE1, len: 447 aa. Equivalent to Rv0131c,
                     len: 447 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 447 aa overlap). Probable fadE1,
                     acyl-CoA dehydrogenase (EC 1.3.99.-), similar to many e.g.
                     ACDS_HUMAN|P16219 acyl-CoA dehydrogenase short-chain
                     specific precursor (412 aa), FASTA scores: opt: 522, E():
                     1.4e-23, (30.1% identity in 425 aa overlap). Also highly
                     similar to MTCI5_28 from Mycobacterium tuberculosis.
                     Protein product from Mb0136c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0136c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MPVRRRAGER LPTVWDFETD PQYQSKLDWV EKFMAEELEP LDLVALDPYD KKNADTMAIL
       61 RPLQRQVKDQ GLWAAHLRPE LGGQGFGQVK LALLNEIIGR SRWAPSAFGC QAPDSGNAEI
      121 LALFGTDEQK ARYLRPLLDG EITSCYSMTE PQGGSDPGLF VTAATRDAAG NGDWIINGEK
      181 WFSTNAKHAS FFIVMAVTKP EARTYEKMSL FIVPADTPGI EIVRNVGVGA ESTRHASHGY
      241 IRYHDVRVPA DHVLGGEGQA FMIAQTRLGG GRIHHAMRTI ALARRAFDMM CERALSRQTR
      301 HGRLADLQMT QEKIADSWIQ IEQFRLLVLR TAWLIDKHHD YQKVRRDIAA VKVAMPQVLH
      361 DVVQRAMHLH GALGVSDEMP FVKMMLAAES LGIADGATEL HKMTVARRTL REYQPVTTLF
      421 PSQHIPTRRA HAEAWLAQRL EHAIAEF
//