LOCUS CAA92184.2 573 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans AcetylCholine Receptor protein. ACCESSION BX284606-3238 PROTEIN_ID CAA92184.2 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="acr-12" /locus_tag="CELE_R01E6.4" /standard_name="R01E6.4a" /note="Product from WormBase gene class acr" /note="Confirmed by transcript evidence" /db_xref="EnsemblGenomes-Gn:WBGene00000051" /db_xref="EnsemblGenomes-Tr:R01E6.4a" /db_xref="GOA:G5EDF1" /db_xref="InterPro:IPR002394" /db_xref="InterPro:IPR006029" /db_xref="InterPro:IPR006201" /db_xref="InterPro:IPR006202" /db_xref="InterPro:IPR018000" /db_xref="InterPro:IPR036719" /db_xref="InterPro:IPR036734" /db_xref="UniProtKB/TrEMBL:G5EDF1" /db_xref="WormBase:WBGene00000051" intron_pos 52:0 (1/11) intron_pos 93:0 (2/11) intron_pos 129:2 (3/11) intron_pos 164:0 (4/11) intron_pos 198:1 (5/11) intron_pos 261:2 (6/11) intron_pos 309:0 (7/11) intron_pos 372:2 (8/11) intron_pos 407:0 (9/11) intron_pos 453:0 (10/11) intron_pos 509:0 (11/11) BEGIN 1 MLYKKRLQMF SFNWALILLV AVGGTNAFKI KRTAKDLESQ LYEDLLFDYN KVPRPVKNSS 61 DILTVDVGAS LIRIIDVDEK NQVLTTNLWL EMKWNDAKLT WTPEKYGGLK TLHIPSDFIW 121 TPDLVLYNNA AGDPDITILT DALVTFEGNV YWQPPAIYKS FCPIDVTWFP YDSQKCEMKF 181 GTWTYTGRYV DLKQLPQEEV VTITKDDNDV EFMQQGMDLS FFYRSAEWDL LSLTSERHSV 241 LYASCCGPEK YVDITYYFGL RRKTLFFTCN LILPCFLISI LTTFVFYLSD HKITFSISIL 301 VTLTVFFLVL IDLMPPTSLV IPMFGRYLIT TMILVALSTV VSVITVNFRF RSGSAHKMSP 361 WIRAVFLKFL PKILLMSRPE KGEVTKQPPL VNAASLVGSN YATAAKAANE YRNKAKGKNN 421 DLMSLRGKPS SQAVLNNTFD MRMRNNDSTV ENRLKPYLCA QNNNAPTVAF RKTKRQKSKS 481 VDDVVFMNLL NQVRFIAEHF RHNELEGEIS DDWTFVAMVL DRLFLIIFSV LNVGTVFIIL 541 ESPSLYDYSK PMNITVPNKP LGQANFYSSW NLK //