LOCUS       CAA84352.1              2186 aa    PRT              HUM 21-OCT-2008
DEFINITION  Homo sapiens voltage-dependent L-type Ca channel alpha
            1 subunit protein.
ACCESSION   Z34821-1
PROTEIN_ID  CAA84352.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6659)
  AUTHORS   Soldatov N.M.
  TITLE     Molecular diversity of L-type Ca2+ channel transcripts in human
            fibroblasts
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89(10), 4628-4632(1992).
   PUBMED   1316612
REFERENCE   2  (bases 1 to 6659)
  AUTHORS   Soldatov N.M.
  TITLE     Genomic structure of human L-type Ca2+ channel
  JOURNAL   Genomics 22(1), 77-87(1994).
   PUBMED   7959794
REFERENCE   3  (bases 1 to 6659)
  AUTHORS   Soldatov N.M.
  TITLE     Functional Expression of Splice Variants of Human L-type Calcium
            Channel (isoform 1 gene)
  JOURNAL   Unpublished.
REFERENCE   4  (bases 1 to 6659)
  AUTHORS   Soldatov N.
  JOURNAL   Submitted (15-JUN-1994) to the INSDC. Nikolai M. Soldatov,
            Pharmacology, University of Bern, Friedbuehlstrasse 49, Bern,
            CH-3010, Switzerland
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000326980"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /dev_stage="fetal"
                     /cell_line="CRL 1475 (ATCC)"
                     /cell_type="fibroblast"
                     /db_xref="taxon:9606"
     protein         /standard_name="CACNL1A1 isoform 1"
                     /function="L-type calcium channel (clone HLCC90) splice
                     variant"
                     /note="composed of exons 1-44, 46-50"
                     /db_xref="GOA:Q13936"
                     /db_xref="H-InvDB:HIT000326980.14"
                     /db_xref="HGNC:HGNC:1390"
                     /db_xref="InterPro:IPR002077"
                     /db_xref="InterPro:IPR005446"
                     /db_xref="InterPro:IPR005451"
                     /db_xref="InterPro:IPR005821"
                     /db_xref="InterPro:IPR014873"
                     /db_xref="InterPro:IPR027359"
                     /db_xref="InterPro:IPR031649"
                     /db_xref="InterPro:IPR031688"
                     /db_xref="PDB:1T0J"
                     /db_xref="PDB:2BE6"
                     /db_xref="PDB:2F3Y"
                     /db_xref="PDB:2F3Z"
                     /db_xref="PDB:2LQC"
                     /db_xref="PDB:3G43"
                     /db_xref="PDB:3OXQ"
                     /db_xref="PDB:5V2P"
                     /db_xref="PDB:5V2Q"
                     /db_xref="PDB:6C0A"
                     /db_xref="PDB:6DAD"
                     /db_xref="PDB:6DAE"
                     /db_xref="PDB:6DAF"
                     /db_xref="UniProtKB/Swiss-Prot:Q13936"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MVNENTRMYI PEENHQGSNY GSPRPAHANM NANAAAGLAP EHIPTPGAAL SWQAAIDAAR
       61 QAKLMGSAGN ATISTVSSTQ RKRQQYGKPK KQGSTTATRP PRALLCLTLK NPIRRACISI
      121 VEWKPFEIII LLTIFANCVA LAIYIPFPED DSNATNSNLE RVEYLFLIIF TVEAFLKVIA
      181 YGLLFHPNAY LRNGWNLLDF IIVVVGLFSA ILEQATKADG ANALGGKGAG FDVKALRAFR
      241 VLRPLRLVSG VPSLQVVLNS IIKAMVPLLH IALLVLFVII IYAIIGLELF MGKMHKTCYN
      301 QEGIADVPAE DDPSPCALET GHGRQCQNGT VCKPGWDGPK HGITNFDNFA FAMLTVFQCI
      361 TMEGWTDVLY WVNDAVGRDW PWIYFVTLII IGSFFVLNLV LGVLSGEFSK EREKAKARGD
      421 FQKLREKQQL EEDLKGYLDW ITQAEDIDPE NEDEGMDEEK PRNMSMPTSE TESVNTENVA
      481 GGDIEGENCG ARLAHRISKS KFSRYWRRWN RFCRRKCRAA VKSNVFYWLV IFLVFLNTLT
      541 IASEHYNQPN WLTEVQDTAN KALLALFTAE MLLKMYSLGL QAYFVSLFNR FDCFVVCGGI
      601 LETILVETKI MSPLGISVLR CVRLLRIFKI TRYWNSLSNL VASLLNSVRS IASLLLLLFL
      661 FIIIFSLLGM QLFGGKFNFD EMQTRRSTFD NFPQSLLTVF QILTGEDWNS VMYDGIMAYG
      721 GPSFPGMLVC IYFIILFICG NYILLNVFLA IAVDNLADAE SLTSAQKEEE EEKERKKLAR
      781 TASPEKKQEL VEKPAVGESK EEKIELKSIT ADGESPPATK INMDDLQPNE NEDKSPYPNP
      841 ETTGEEDEEE PEMPVGPRPR PLSELHLKEK AVPMPEASAF FIFSSNNRFR LQCHRIVNDT
      901 IFTNLILFFI LLSSISLAAE DPVQHTSFRN HILFYFDIVF TTIFTIEIAL KILGNADYVF
      961 TSIFTLEIIL KMTAYGAFLH KGSFCRNYFN ILDLLVVSVS LISFGIQSSA INVVKILRVL
     1021 RVLRPLRAIN RAKGLKHVVQ CVFVAIRTIG NIVIVTTLLQ FMFACIGVQL FKGKLYTCSD
     1081 SSKQTEAECK GNYITYKDGE VDHPIIQPRS WENSKFDFDN VLAAMMALFT VSTFEGWPEL
     1141 LYRSIDSHTE DKGPIYNYRV EISIFFIIYI IIIAFFMMNI FVGFVIVTFQ EQGEQEYKNC
     1201 ELDKNQRQCV EYALKARPLR RYIPKNQHQY KVWYVVNSTY FEYLMFVLIL LNTICLAMQH
     1261 YGQSCLFKIA MNILNMLFTG LFTVEMILKL IAFKPKGYFS DPWNVFDFLI VIGSIIDVIL
     1321 SETNHYFCDA WNTFDALIVV GSIVDIAITE VNPAEHTQCS PSMNAEENSR ISITFFRLFR
     1381 VMRLVKLLSR GEGIRTLLWT FIKSFQALPY VALLIVMLFF IYAVIGMQVF GKIALNDTTE
     1441 INRNNNFQTF PQAVLLLFRC ATGEAWQDIM LACMPGKKCA PESEPSNSTE GETPCGSSFA
     1501 VFYFISFYML CAFLIINLFV AVIMDNFDYL TRDWSILGPH HLDEFKRIWA EYDPEAKGRI
     1561 KHLDVVTLLR RIQPPLGFGK LCPHRVACKR LVSMNMPLNS DGTVMFNATL FALVRTALRI
     1621 KTEGNLEQAN EELRAIIKKI WKRTSMKLLD QVVPPAGDDE VTVGKFYATF LIQEYFRKFK
     1681 KRKEQGLVGK PSQRNALSLQ AGLRTLHDIG PEIRRAISGD LTAEEELDKA MKEAVSAASE
     1741 DDIFRRAGGL FGNHVSYYQS DGRSAFPQTF TTQRPLHINK AGSSQGDTES PSHEKLVDST
     1801 FTPSSYSSTG SNANINNANN TALGRLPRPA GYPSTVSTVE GHGPPLSPAI RVQEVAWKLS
     1861 SNRCHSRESQ AAMAGQEETS QDETYEVKMN HDTEACSEPS LLSTEMLSYQ DDENRQLTLP
     1921 EEDKRDIRQS PKRGFLRSAS LGRRASFHLE CLKRQKDRGG DISQKTVLPL HLVHHQALAV
     1981 AGLSPLLQRS HSPASFPRPF ATPPATPGSR GWPPQPVPTL RLEGVESSEK LNSSFPSIHC
     2041 GSWAETTPGG GGSSAARRVR PVSLMVPSQA GAPGRQFHGS ASSLVEAVLI SEGLGQFAQD
     2101 PKFIEVTTQE LADACDMTIE EMESAADNIL SGGAPQSPNG ALLPFVNCRD AGQDRAGGEE
     2161 DAGCVRARGA PSEEELQDSR VYVSSL
//