LOCUS       CAA84342.1              2157 aa    PRT              HUM 07-OCT-2008
DEFINITION  Homo sapiens voltage-dependent L-type Ca channel alpha
            1 subunit protein.
ACCESSION   Z34811-1
PROTEIN_ID  CAA84342.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4726;4784 to 6572)
  AUTHORS   Soldatov N.M.
  TITLE     Molecular diversity of L-type Ca2+ channel transcripts in human
            fibroblasts
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89(10), 4628-4632(1992).
   PUBMED   1316612
REFERENCE   2  (bases 1 to 6572)
  AUTHORS   Soldatov N.M.
  TITLE     Genomic structure of human L-type Ca2+ channel
  JOURNAL   Genomics 22(1), 77-87(1994).
   PUBMED   7959794
REFERENCE   3  (bases 1 to 6572)
  AUTHORS   Soldatov N.M.
  TITLE     Functional Expression of Splice Variants of Human L-type Calcium
            Channel (isoform 1 gene)
  JOURNAL   Unpublished.
REFERENCE   4  (bases 1 to 6572)
  AUTHORS   Soldatov N.
  JOURNAL   Submitted (15-JUN-1994) to the INSDC. Nikolai M. Soldatov,
            Pharmacology, University of Bern, Friedbuehlstrasse 49, Bern,
            CH-3010, Switzerland
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000326970"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /dev_stage="fetal"
                     /cell_line="CRL 1475 (ATCC)"
                     /cell_type="fibroblast"
                     /db_xref="taxon:9606"
     protein         /standard_name="CACNL1A1 isoform 1"
                     /function="L-type calcium channel (clone HLCC71) splice
                     variant"
                     /note="composed of exons 1-21, 23-30, 32-40, 41A, 42-44,
                     46-50"
                     /db_xref="GOA:Q13936"
                     /db_xref="H-InvDB:HIT000326970.12"
                     /db_xref="HGNC:HGNC:1390"
                     /db_xref="InterPro:IPR002077"
                     /db_xref="InterPro:IPR005446"
                     /db_xref="InterPro:IPR005451"
                     /db_xref="InterPro:IPR005821"
                     /db_xref="InterPro:IPR014873"
                     /db_xref="InterPro:IPR027359"
                     /db_xref="InterPro:IPR031649"
                     /db_xref="InterPro:IPR031688"
                     /db_xref="PDB:1T0J"
                     /db_xref="PDB:2BE6"
                     /db_xref="PDB:2F3Y"
                     /db_xref="PDB:2F3Z"
                     /db_xref="PDB:2LQC"
                     /db_xref="PDB:3G43"
                     /db_xref="PDB:3OXQ"
                     /db_xref="PDB:5V2P"
                     /db_xref="PDB:5V2Q"
                     /db_xref="PDB:6C0A"
                     /db_xref="PDB:6DAD"
                     /db_xref="PDB:6DAE"
                     /db_xref="PDB:6DAF"
                     /db_xref="UniProtKB/Swiss-Prot:Q13936"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MVNENTRMYI PEENHQGSNY GSPRPAHANM NANAAAGLAP EHIPTPGAAL SWQAAIDAAR
       61 QAKLMGSAGN ATISTVSSTQ RKRQQYGKPK KQGSTTATRP PRALLCLTLK NPIRRACISI
      121 VEWKPFEIII LLTIFANCVA LAIYIPFPED DSNATNSNLE RVEYLFLIIF TVEAFLKVIA
      181 YGLLFHPNAY LRNGWNLLDF IIVVVGLFSA ILEQATKADG ANALGGKGAG FDVKALRAFR
      241 VLRPLRLVSG VPSLQVVLNS IIKAMVPLLH IALLVLFVII IYAIIGLELF MGKMHKTCYN
      301 QEGIADVPAE DDPSPCALET GHGRQCQNGT VCKPGWDGPK HGITNFDNFA FAMLTVFQCI
      361 TMEGWTDVLY WVNDAVGRDW PWIYFVTLII IGSFFVLNLV LGVLSGEFSK EREKAKARGD
      421 FQKLREKQQL EEDLKGYLDW ITQAEDIDPE NEDEGMDEEK PRNMSMPTSE TESVNTENVA
      481 GGDIEGENCG ARLAHRISKS KFSRYWRRWN RFCRRKCRAA VKSNVFYWLV IFLVFLNTLT
      541 IASEHYNQPN WLTEVQDTAN KALLALFTAE MLLKMYSLGL QAYFVSLFNR FDCFVVCGGI
      601 LETILVETKI MSPLGISVLR CVRLLRIFKI TRYWNSLSNL VASLLNSVRS IASLLLLLFL
      661 FIIIFSLLGM QLFGGKFNFD EMQTRRSTFD NFPQSLLTVF QILTGEDWNS VMYDGIMAYG
      721 GPSFPGMLVC IYFIILFICG NYILLNVFLA IAVDNLADAE SLTSAQKEEE EEKERKKLAR
      781 TASPEKKQEL VEKPAVGESK EEKIELKSIT ADGESPPATK INMDDLQPNE NEDKSPYPNP
      841 ETTGEEDEEE PEMPVGPRPR PLSELHLKEK AVPMPEASAF FIFSSNNRFR LQCHRIVNDT
      901 IFTNLILFFI LLSSISLAAE DPVQHTSFRN HILFYFDIVF TTIFTIEIAL KMTAYGAFLH
      961 KGSFCRNYFN ILDLLVVSVS LISFGIQSSA INVVKILRVL RVLRPLRAIN RAKGLKHVVQ
     1021 CVFVAIRTIG NIVIVTTLLQ FMFACIGVQL FKGKLYTCSD SSKQTEAECK GNYITYKDGE
     1081 VDHPIIQPRS WENSKFDFDN VLAAMMALFT VSTFEGWPEL LYRSIDSHTE DKGPIYNYRV
     1141 EISIFFIIYI IIIAFFMMNI FVGFVIVTFQ EQGEQEYKNC ELDKNQRQCV EYALKARPLR
     1201 RYIPKNQHQY KVWYVVNSTY FEYLMFVLIL LNTICLAMQH YGQSCLFKIA MNILNMLFTG
     1261 LFTVEMILKL IAFKPKHYFC DAWNTFDALI VVGSIVDIAI TEVNPAEHTQ CSPSMNAEEN
     1321 SRISITFFRL FRVMRLVKLL SRGEGIRTLL WTFIKSFQAL PYVALLIVML FFIYAVIGMQ
     1381 VFGKIALNDT TEINRNNNFQ TFPQAVLLLF RCATGEAWQD IMLACMPGKK CAPESEPSNS
     1441 TEGETPCGSS FAVFYFISFY MLCAFLIINL FVAVIMDNFD YLTRDWSILG PHHLDEFKRI
     1501 WAEYDPEAKG RIKHLDVVTL LRRIQPPLGF GKLCPHRVAC KRLVSMNMPL NSDGTVMFNA
     1561 TLFALVRTAL RIKTEEGPSP SEAHQGAEDP FRPAGNLEQA NEELRAIIKK IWKRTSMKLL
     1621 DQVVPPAGDD EVTVGKFYAT FLIQEYFRKF KKRKEQGLVG KPSQRNALSL QAGLRTLHDI
     1681 GPEIRRAISG DLTAEEELDK AMKEAVSAAS EDDIFRRAGG LFGNHVSYYQ SDGRSAFPQT
     1741 FTTQRPLHIN KAGSSQGDTE SPSHEKLVDS TFTPSSYSST GSNANINNAN NTALGRLPRP
     1801 AGYPSTVSTV EGHGPPLSPA IRVQEVAWKL SSNRCHSRES QAAMAGQEET SQDETYEVKM
     1861 NHDTEACSEP SLLSTEMLSY QDDENRQLTL PEEDKRDIRQ SPKRGFLRSA SLGRRASFHL
     1921 ECLKRQKDRG GDISQKTVLP LHLVHHQALA VAGLSPLLQR SHSPASFPRP FATPPATPGS
     1981 RGWPPQPVPT LRLEGVESSE KLNSSFPSIH CGSWAETTPG GGGSSAARRV RPVSLMVPSQ
     2041 AGAPGRQFHG SASSLVEAVL ISEGLGQFAQ DPKFIEVTTQ ELADACDMTI EEMESAADNI
     2101 LSGGAPQSPN GALLPFVNCR DAGQDRAGGE EDAGCVRARG APSEEELQDS RVYVSSL
//