LOCUS       CAA68666.1               415 aa    PRT              HUM 07-OCT-2008
DEFINITION  Homo sapiens protein ( Human mRNA for Arg-Serpin (plasminogen
            activator-inhibitor 2, PAI-2). ).
ACCESSION   Y00630-1
PROTEIN_ID  CAA68666.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1900)
  AUTHORS   Webb A.C.
  JOURNAL   Submitted (12-JUN-1987) to the INSDC. Andrew C. Webb, Department of
            Biological Sciences, Wellesley College, Wellesley, MA 02181, USA.
REFERENCE   2
  AUTHORS   Webb A.C., Collins K.L., Snyder S.F., Alexander S.J.,
            Rosenwasser L.J., Eddy R.L., Shows T.B., Auron P.E.
  TITLE     Human monocyte Arg-Serpin cDNA. Sequence, chromosomal assignment,
            and homology to plasminogen activator-inhibitor
  JOURNAL   J. Exp. Med. 166(1), 77-94(1987).
   PUBMED   3496414
COMMENT     *source=LPS-stimulated monocytes; clone=pcD-1214
            PAI-2 is a member CC   of the serine protease inhibitor (serpin)
            superfamily. It inhibits urokinase-type plasminogen activator.
            The monocyte derived PAI-2 is distinct from the endothelial
            cell-derived PAI-1.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000325296"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     protein         /note="PAI-2 precursor (AA -22 to 393)"
                     /db_xref="GOA:P05120"
                     /db_xref="H-InvDB:HIT000325296.14"
                     /db_xref="HGNC:HGNC:8584"
                     /db_xref="InterPro:IPR000215"
                     /db_xref="InterPro:IPR015556"
                     /db_xref="InterPro:IPR023795"
                     /db_xref="InterPro:IPR023796"
                     /db_xref="InterPro:IPR036186"
                     /db_xref="InterPro:IPR042178"
                     /db_xref="InterPro:IPR042185"
                     /db_xref="PDB:1BY7"
                     /db_xref="PDB:1JRR"
                     /db_xref="PDB:2ARQ"
                     /db_xref="PDB:2ARR"
                     /db_xref="UniProtKB/Swiss-Prot:P05120"
BEGIN
        1 MEDLCVANTL FALNLFKHLA KASPTQNLFL SPWSISSTMA MVYMGSRGST EDQMAKVLQF
       61 NEVGANAVTP MTPENFTSCG FMQQIQKGSY PDAILQAQAA DKIHSSFRSL SSAINASTGN
      121 YLLESVNKLF GEKSASFREE YIRLCQKYYS SEPQAVDFLE CAEEARKKIN SWVKTQTKGK
      181 IPNLLPEGSV DGDTRMVLVN AVYFKGKWKT PFEKKLNGLY PFRVNSAQRT PVQMMYLREK
      241 LNIGYIEDLK AQILELPYAG DVSMFLLLPD EIADVSTGLE LLESEITYDK LNKWTSKDKM
      301 AEDEVEVYIP QFKLEEHYEL RSILRSMGME DAFNKGRANF SGMSERNDLF LSEVFHQAMV
      361 DVNEEGTEAA AGTGGVMTGR TGHGGPQFVA DHPFLFLIMH KITNCILFFG RFSSP
//