LOCUS       BBK52284.1               865 aa    PRT              BCT 04-APR-2020
DEFINITION  Escherichia coli O145:H28 DNA topoisomerase I protein.
ACCESSION   AP019706-1696
PROTEIN_ID  BBK52284.1
SOURCE      Escherichia coli O145:H28
  ORGANISM  Escherichia coli O145:H28
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5488534)
  AUTHORS   Nakamura,K., Murase,K., Toyoda,A., Itoh,T., Yoshino,S., Lee,K.,
            Iyoda,S., Ohnishi,M., Ooka,T., Ogura,Y. and Hayashi,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JUN-2019) to the DDBJ/EMBL/GenBank databases.
            Contact:Keiji Nakamura
            Faculty of Medical Sciences, Kyushu University; Higashi-ku
            Maidashi 3-1-1, Fukuoka, Fukuoka 812-8582, Japan
REFERENCE   2  
  AUTHORS   Nakamura,K., Murase,K., Sato,M.P., Toyoda,A., Itoh,T.,
            Mainil,J.G., Pierard,D., Yoshino,S., Kimata,K., Isobe,J., Seto,K.,
            Etoh,Y., Narimatsu,H., Saito,S., Yatsuyanagi,J., Lee,K., Iyoda,S.,
            Ohnishi,M., Ooka,T., Gotoh,Y., Ogura,Y. and Hayashi,T.
  TITLE     Differential dynamics and impacts of prophages and plasmids on the
            pangenome and virulence factor repertoires of Shiga
            toxin-producing Escherichia coli O145:H28
  JOURNAL   Microb Genom 6, e000323 (2020)
  REMARK    Publication Status: Online-Only
            DOI:10.1099/mgen.0.000323
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method       :: Canu v. 1.5
            Genome Coverage       :: 150x
            Sequencing Technology :: Illumina MiSeq; PacBio RS II
            ##Genome-Assembly-Data-END##
FEATURES             Qualifiers
     source          /collection_date="2011"
                     /country="Japan:Fukushima"
                     /db_xref="taxon:1078034"
                     /isolation_source="human feces"
                     /mol_type="genomic DNA"
                     /organism="Escherichia coli O145:H28"
                     /serovar="O145:H28"
                     /strain="112648"
     protein         /EC_number="5.99.1.2"
                     /gene="topA"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:INSD:AAN80207.1"
                     /locus_tag="EC112648_1696"
                     /transl_table=11
BEGIN
        1 MGKALVIVES PAKAKTINKY LGSDYVVKSS VGHIRDLPTS GSAAKKSADS TSTKTAKKPK
       61 KDERGALVNR MGVDPWHNWE AHYEVLPGKE KVVSELKQLA EKADHIYLAT DLDREGEAIA
      121 WHLREVIGGD DARYSRVVFN EITKNAIRQA FNKPGELNID RVNAQQARRF MDRVVGYMVS
      181 PLLWKKIARG LSAGRVQSVA VRLVVERERE IKAFVPEEFW EVDASTTTPS GEALALQVTH
      241 QNDKPFRPVN KEQTQAAVSL LEKARYSVLE REDKPTTSKP GAPFITSTLQ QAASTRLGFG
      301 VKKTMMMAQR LYEAGYITYM RTDSTNLSQD AVNMVRGYIS DNFGKKYLPE SPNQYASKEN
      361 SQEAHEAIRP SDVNVMAESL KDMEADAQKL YQLIWRQFVA CQMTPAKYDS TTLTVGAGDF
      421 RLKARGRILR FDGWTKVMPA LRKGDEDRIL PAVDKGDALT LVELTPAQHF TKPPARFSEA
      481 SLVKELEKRG IGRPSTYASI ISTIQDRGYV RVENRRFYAE KMGEIVTDRL EENFRELMNY
      541 DFTAQMENSL DQVANHEAEW KAVLDHFFSD FTQQLDKAEK DPEEGGMRPN QMVLTSIDCP
      601 TCGRKMGIRT ASTGVFLGCS GYALPPKERC KTTINLVPEN EVLNVLEGED AETNALRAKR
      661 RCPKCGTAMD SYLIDPKRKL HVCGNNPTCD GYEIEEGEFR IKGYDGPIVE CEKCGSEMHL
      721 KMGRFGKYMA CTNEECKNTR KILRNGEVAP PKEDPVPLPE LPCEKSDAYF VLRDGAAGVF
      781 LAANTFPKSR ETRAPLVEEL YRFRDRLPEK LRYLADAPQQ DPEGNKTMVR FSRKTKQQYV
      841 SSEKDGKATG WSAFYVDGKW VEGKK
//