LOCUS       BAA34202.1              1435 aa    PRT              HUM 06-NOV-1998
DEFINITION  Homo sapiens DNA topoisomerase II binding protein protein.
ACCESSION   AB019397-1
PROTEIN_ID  BAA34202.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5255)
  AUTHORS   Yamane,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-1998) to the DDBJ/EMBL/GenBank databases.
            Contact:Kazuhiko Yamane
            Japanese Foundation for Cancer Research, Cancer Chemotherapy
            Center; 1-37-1 Kami-ikebukuro, Toshima-ku, Tokyo 170-8455, Japan
REFERENCE   2  
  AUTHORS   Yamane,K., Kawabata,M. and Tsuruo,T.
  TITLE     A DNA topoisomerase II binding protein with eight repeating
            regions similar to DNA repair enzymes and to a cell cycle regulator
  JOURNAL   Eur. J. Biochem. 250, 794-799 (1998)
COMMENT     
FEATURES             Qualifiers
     source          /cell_line="HeLa"
                     /db_xref="H-InvDB:HIT000058583"
                     /db_xref="taxon:9606"
                     /mol_type="mRNA"
                     /organism="Homo sapiens"
     protein         /gene="TopBP1"
                     /transl_table=1
BEGIN
        1 MHHQRCVPRA EHPVYNMVMS DVTISCTSLE KEKREEVHKY VQMMGGRVYR DLNVSVTHLI
       61 AGEVGSKKYL VAANLKKPIL LPSWIKTLWE KSQEKKITRY TDINMEDFKC PIFLGCIICV
      121 TGLCGLDRKE VQQLTVKHGG QYMGQLKMNE CTHLIVQEPK GQKYECAKRW NVHCVTTQWF
      181 FDSIEKGFCQ DESIYKTEPR PEAKTMPNSS TPTSQINTID SRTLSDVSNI SNINASCVSE
      241 SICNSLNSKL EPTLENLENL DVSAFQAPED LLDGCRIYLC GFSGRKLDKL RRLINSGGGV
      301 RFNQLNEDVT HVIVGDYDDE LKQFWNKSAH RPHVVGAKWL LECFSKGYML SEEPYIHANY
      361 QPVEIPVSHQ PESKAALLKK KNSSFSKKDF APSEKHEQAD EDLLSQYENG SSTVVEAKTS
      421 EARPFNDSTH AEPLNDSTHI SLQEENQSSV SHCVPDVSTI TEEGLFSQKS FLVLGFSNEN
      481 ESNIANIIKE NAGKIMSLLS RTVADYAVVP LLGCEVEATV GEVVTNTWLV TCIDYQTLFD
      541 PKSNPLFTPV PVMTGMTPLE DCVISFSQCA GAEKESLTFL ANLLGASVQE YFVRKSNAKK
      601 GMFASTHLIL KERGGSKYEA AKKWNLPAVT IAWLLETART GKRADESHFL IENSTKEERS
      661 LETEITNGIN LNSDTAEHPG TRLQTHRKTV VTPLDMNRFQ SKAFRAVVSQ HARQVAASPA
      721 VGQPLQKEPS LHLDTPSKFL SKDKLFKPSF DVKDALAALE TPGRPSQQKR KPSTPLSEVI
      781 VKNLQLALAN SSRNAVALSA SPQLKEAQSE KEEAPKPLHK VVVCVSKKLS KKQSELNGIA
      841 ASLGADYRWS FDETVTHFIY QGRPNDTNRE YKSVKERGVH IVSEHWLLDC AQECKHLPES
      901 LYPHTYNPKM SLDISAVQDG RLCNSRLLSA VSSTKDDEPD PLILEENDVD NMATNNKESA
      961 PSNGSGKNDS KGVLTQTLEM RENFQKQLQE IMSATSIVKP QGQRTSLSRS GCNSASSTPD
     1021 STRSARSGRS RVLEALRQSR QTVPDVNTEP SQNEQIIWDD PTAREERARL ASNLQWPSCP
     1081 TQYSELQVDI QNLEDSPFQK PLHDSEIAKQ AVCDPGNIRV TEAPKHPISE ELETPIKDSH
     1141 LIPTPQAPSI AFPLANPPVA PHPREKIITI EETHEELKKQ YIFQLSSLNP QERIDYCHLI
     1201 EKLGGLVIEK QCFDPTCTHI VVGHPLRNEK YLASVAAGKW VLHRSYLEAC RTAGHFVQEE
     1261 DYEWGSSSIL DVLTGINVQQ RRLALAAMRW RKKIQQRQES GIVEGAFSGW KVILHVDQSR
     1321 EAGFKRLLQS GGAKVLPGHS VPLFKEATHL FSDLNKLKPD DSGVNIAEAA AQNVYCLRTE
     1381 YIADYLMQES PPHVENYCLP EAISFIQNNK ELGTGLSQKR KAPTEKNKIK RPRVH
//