LOCUS       BAA02632.1               392 aa    PRT              HUM 12-SEP-2008
DEFINITION  Homo sapiens alanine:glyoxylate aminotransferase protein.
ACCESSION   D13368-1
PROTEIN_ID  BAA02632.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1325)
  AUTHORS   Minatogawa,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-1992) to the DDBJ/EMBL/GenBank databases.
            Contact:Yohsuke Minatogawa
            Wakayama Medical College, Department of Biochemistry; 9-27,
            Wakayama, Wakayama 640, Japan
REFERENCE   2  
  AUTHORS   Takada,Y., Kaneko,N., Esumi,H., Purdue,P.E. and Danpure,C.J.
  TITLE     Human peroxisomal L-alanine:glyoxylate
            aminotransferase:Evolutionary loss of a mitochondrial targeting
            signal by point mutation
  JOURNAL   Biochem. J. 268, 517-520 (1990)
REFERENCE   3  
  AUTHORS   Minatogawa,Y., Tone,S., Allsop,J., Purdue,E.P., Takada,Y.,
            Danpure,C.J. and Kido,R.
  TITLE     A serine-to-phenylalanine substitution leads to loss of alanine:
            glyoxylate aminotransferase catalytic activity and
            immunoreactivity in a patient with primary hyperoxaluria type 1
  JOURNAL   Hum. Mol. Genet. 1, 643-644 (1992)
COMMENT     
FEATURES             Qualifiers
     source          /chromosome="2"
                     /clone="P2-3, P2-7"
                     /db_xref="H-InvDB:HIT000100497"
                     /db_xref="taxon:9606"
                     /isolate="Patient 2"
                     /map="2q36-q37"
                     /mol_type="mRNA"
                     /note="patient of primary hyperoxaluria type 1"
                     /organism="Homo sapiens"
                     /tissue_type="liver"
     protein         /EC_number="2.6.1.44"
                     /gene="AGXT"
BEGIN
        1 MASHKLLVTP PKALLKPLSI PNQLLLGPGP SNLPPRIMAA GGLQMIGSMS KDMYQIMDEI
       61 KEGIQYVFQT RNPLTLVISG SGHCALEAAL VNVLEPGDSF LVGANGIWGQ RAVDIGERIG
      121 ARVHPMTKDP GGHYTLQEVE EGLAQHKPVL LFLTHGESST GVLQPLDGFG ELCHRYKCLL
      181 LVDSVAFLGG TPLYMDRQGI DILYSGSQKA LNAPPGTSLI SFSDKAKKKM YSRKTKPFSF
      241 YLDIKWLANF WGCDDQPRMY HHTIPVISLY SLRESLALIA EQGLENSWRQ HREAAAYLHG
      301 RLQALGLQLF VKDPALRLPT VTTVAVPAGY DWRDIVSYVI DHFDIEIMGG LGPSTGKVLR
      361 IGLLGCNATR ENVDRVTEAL RAALQHCPKK KL
//