LOCUS       AJF01620.1               560 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative fatty-acid-
            CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-
            CoA synthase) protein.
ACCESSION   CP007027-276
PROTEIN_ID  AJF01620.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="fadD2"
                     /locus_tag="Y980_0270"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00455"
                     /note="Rv0270, (MTCY06A4.14) Probable fadD2,fatty-acid-CoA
                     synthetase, similar to many e.g. LCFA_ECOLI|P29212
                     long-chain-fatty-acid--CoA ligase from Escherichia coli
                     (561 aa). Also similar to others from Mycobacterium
                     tuberculosis e.g. MTCY493_2,MTCY8D5_9, MTCY6G11_8, etc.
                     Contains PS00455 Putative AMP-binding domain signature."
                     /transl_table=11
                     /db_xref="GOA:L7N5E5"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="UniProtKB/TrEMBL:L7N5E5"
BEGIN
        1 MPNLTDLPGQ AVSKLQKSIG QYVARGTAEL HYLRKIIESG AIGLEPPLNY AALAADIRKW
       61 GEVGMLPSHN ARRAPNRAAV IDEEGTLTFS ELDEAAHAVA NGLLAKGVRA GDGVAILARN
      121 HRWFVIANYG AARVGARIIL LNSEFSGPQI KEVSDREGAK VIIYDDEYTK AVSLAQPPLG
      181 KLRALGVNPD DDKPSGSSDE TLAELIAHSS TAPAPKASRR ASIIILTSGT TGTPKGANRN
      241 TPPTLAPIGG ILSHVPFKAG EVTLLPSPMF HALGYMHAAL AMFLGSTLVL RRRFKPALVL
      301 EDIEKHKATS MVVVPVMLSR ILDQLEKTEP KPDLSSLKIV FVSGSQLGAE LATRALGDLG
      361 PVIYNMYGST EVAFATIAGP KDLQFNPSTV GPVVKGVTVK ILDENGNEVP QGAVGRIFVG
      421 NAFPFEGYTG GGGKQIIDGL LSSGDVGYFD ERGLLYVSGR DDEMIVSGGE NVFPAEVEDL
      481 ISGHPDVVEA AAIGVDDKEF GARLRAFVVK KPGADLDEDT IKQYVRDHLA RYKVPREVIF
      541 LDELPRNPTG KVLKRELRKL
//