LOCUS       AJF01598.1               646 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative succinate
            dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase)
            protein.
ACCESSION   CP007027-254
PROTEIN_ID  AJF01598.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /locus_tag="Y980_0248c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00017"
                     /inference="protein motif:PROSITE:PS00141"
                     /note="Rv0248c, (MTV034.14c) Probable succinate
                     dehydrogenase, flavoprotein subunit, highly similar to
                     flavoprotein subunit of various succinate dehydrogenases
                     e.g. M88696|RIRSDHA_1 flavoprotein from Rickettsia
                     prowazekii (596 aa). Also similar to truncated U00022_17
                     flavoprotein from Mycobacterium leprae (401 aa). Note that
                     succinate dehydrogenase forms generally part of an enzyme
                     complex containing four subunits: a flavoprotein (Rv0248c
                     ?), an iron-sulfur (Rv0247c ?), and two hydrophobic anchor
                     proteins (Rv0249c ?)."
                     /transl_table=11
                     /db_xref="GOA:L7N5C5"
                     /db_xref="HSSP:P00363"
                     /db_xref="InterPro:IPR003953"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="InterPro:IPR014006"
                     /db_xref="InterPro:IPR015939"
                     /db_xref="InterPro:IPR027477"
                     /db_xref="UniProtKB/TrEMBL:L7N5C5"
BEGIN
        1 MVEVERHSYD VVVIGAGGAG LRAVIEARER GLKVAVVCKS LFGKAHTVMA EGGCAAAMGN
       61 ANPKDNWKTH FGDTMRGGKF LNNWRMAELH AKEAPDRVWE LETYGALFDR TDDGRISQRN
      121 FGGHTYPRLA HVGDRTGLEL IRTLQQKVVS LQQEDHAELG DYEARIKVFA ECTITELLKD
      181 QGAIAGAFGY WRESGRFIVF EAPAVVLATG GIGKSFKVTS NSWEYTGDGH ALALRAGATL
      241 INMEFVQFHP TGMVWPPSVK GILVTEGVRG DGGVLKNSEN SRFMFDYIPP VFKGQYAETE
      301 EEADQWLKDN DSARRTPDLL PRDEVARAIN SEVKAGRGTP HGGVYLDIAS RLTPAEIKRR
      361 LPSMYHQFKE LAEVDITTQA MEVGPTCHYV MGGVEVDADT GAATVPGLFA AGECAGGMHG
      421 SNRLGGNSLS DLLVFGRRAG LGAADYVRAL SSRPAVSAEA IDAAAQQALS PFEGPKDGSA
      481 PENPYALHMD LQYVMNDLVG IIRNADEISR ALTLLAELWS RYHNVLVEGH RQYNPGWNLS
      541 IDLRNMLLVS ECVARAALQR TESRGGHTRD DHPGMDPNWR RILLVCRATE TMGTGGSGSG
      601 DSNCHINVTQ QLQTPMRPDL LELFEISELE KYYTDEELAE HPGRRG
//