LOCUS       AJF01597.1               248 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative succinate
            dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase)
            protein.
ACCESSION   CP007027-253
PROTEIN_ID  AJF01597.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /locus_tag="Y980_0247c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00197"
                     /note="Rv0247c, (MTV034.13c) Probable succinate
                     dehydrogenase, iron-sulfur subunit, highly similar to
                     CAC44313.1|AL596043 putative succinate dehydrogenase
                     iron-sulfur subunit from Streptomyces coelicolor (259 aa);
                     and similar to iron-sulphur protein subunits of fumarate
                     reductase or succinate dehydrogenases from many bacteria
                     e.g. NP_147618.1|7521083|B72691 fumarate reductase
                     iron-sulfur protein from Aeropyrum pernix (305 aa);
                     NP_069516.1|2649932|AAB90556.1|AE001057 succinate
                     dehydrogenase iron-sulfur subunit B (sdhB) from
                     Archaeoglobus fulgidus (236 aa); etc. Also similar to
                     Q10761|FRDB_MYCTU|7431693|F70762 fumarate reductase
                     iron-sulfur protein from Mycobacterium tuberculosis (247
                     aa). Contains PS00197 2Fe-2S ferredoxins,iron-sulfur
                     binding region signature. Note that succinate
                     dehydrogenase forms generally part of an enzyme complex
                     containing four subunits: a flavoprotein (Rv0248c ?), an
                     iron-sulfur (Rv0247c ?), and two hydrophobic anchor
                     proteins (Rv0249c ?)."
                     /transl_table=11
                     /db_xref="GOA:L7N4K2"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR004489"
                     /db_xref="InterPro:IPR006058"
                     /db_xref="InterPro:IPR009051"
                     /db_xref="InterPro:IPR012285"
                     /db_xref="InterPro:IPR012675"
                     /db_xref="InterPro:IPR017896"
                     /db_xref="UniProtKB/TrEMBL:L7N4K2"
BEGIN
        1 MTYSASMRVW RGDESCGELR EFTVEVNEGE VVLDVILRLQ QTQTPDLAVR WNCKAGKCGS
       61 CSAEINGKPR LMCMTRMSTF DEDEIVTVTP MRTFPVIRDL VTDVSFNYQK AREIPSFAPP
      121 KELQPSEYRM AQVDVARSQE FRKCIECFLC QNVCHVVRDH EENKDAFAGP RFLMRIAELE
      181 MHPLDTRDRR SQAQEEHGLG YCNITKCCTE VCPENIKITD NALIPMKERV ADRKYDPVVW
      241 LGSKLFRR
//