LOCUS       AJF01592.1               454 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative 3-oxoacyl-
            [acyl-carrier protein] reductase FabG4 (3-ketoacyl-acyl
            carrier protein reductase) protein.
ACCESSION   CP007027-248
PROTEIN_ID  AJF01592.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="fabG4"
                     /locus_tag="Y980_0242c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00061"
                     /note="Rv0242c, (MTV034.08c) Probable
                     fabG4,3-oxoacyl-[acyl-carrier protein] reductase,
                     equivalent to 3063883|CAA18568.1|AL022486|MLCB1883_13|T448
                     78 3-oxoacyl-[acyl-carrier protein] reductase homolog from
                     Mycobacterium leprae (454 aa). C-terminal part highly
                     similar to many FabG proteins e.g. U39441|VHU3944 1_2 from
                     Vibrio harveyi (244 aa); U91631|PAU91631_3 from
                     Pseudomonas aeruginosa (247 aa). Has N-terminal extension
                     of ~200 aa and C-terminal part contains PS00061
                     Short-chain dehydrogenases/reductases family signature.
                     Belongs to the short-chain dehydrogenases/reductases (SDR)
                     family."
                     /transl_table=11
                     /db_xref="GOA:O53665"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="PDB:3M1L"
                     /db_xref="PDB:3Q6I"
                     /db_xref="PDB:3V1T"
                     /db_xref="PDB:3V1U"
                     /db_xref="PDB:4FW8"
                     /db_xref="UniProtKB/TrEMBL:O53665"
BEGIN
        1 MAPKRSSDLF SQVVNSGPGS FLARQLGVPQ PETLRRYRAG EPPLTGSLLI GGAGRVVEPL
       61 RAALEKDYDL VGNNLGGRWA DSFGGLVFDA TGITEPAGLK GLHEFFTPVL RNLGRCGRVV
      121 VVGGTPEAAA STNERIAQRA LEGFTRSLGK ELRRGATTAL VYLSPDAKPA ATGLESTMRF
      181 LLSAKSAYVD GQVFSVGADD STPPADWEKP LDGKVAIVTG AARGIGATIA EVFARDGAHV
      241 VAIDVESAAE NLAETASKVG GTALWLDVTA DDAVDKISEH LRDHHGGKAD ILVNNAGITR
      301 DKLLANMDDA RWDAVLAVNL LAPLRLTEGL VGNGSIGEGG RVIGLSSIAG IAGNRGQTNY
      361 ATTKAGMIGI TQALAPGLAA KGITINAVAP GFIETQMTAA IPLATREVGR RLNSLLQGGQ
      421 PVDVAEAIAY FASPASNAVT GNVIRVCGQA MIGA
//