LOCUS       AJF01591.1               280 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative 3-hydroxyacyl-
            thioester dehydratase HtdX protein.
ACCESSION   CP007027-247
PROTEIN_ID  AJF01591.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="htdX"
                     /locus_tag="Y980_0241c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0241c, (MTV034.07c) Probable
                     htdX,3-hydroxyacyl-thioester dehydratase (See Gurvitz et
                     al.,2009), highly similar to
                     MLCB1883.17c|T44876063881|CAA18566.1|AL022486 hypothetical
                     protein from Mycobacterium leprae (280 aa); and
                     CAC32097.1|AL583926 conserved hypothetical protein from
                     Mycobacterium leprae (300 aa). Shows structural similarity
                     to six others in Mycobacterium tuberculosis (see Castell
                     et al (2005) below). Also similar to proteins from other
                     organisms e.g. CAB77291.1|AL160312 putative dehydratase
                     from Streptomyces coelicolor (291 aa); part of
                     BAA92930.1|AB032743 fatty acid synthetase beta subunit
                     from Pichia angusta (2060 aa). Predicted to be an outer
                     membrane protein (See Song et al., 2008)."
                     /transl_table=11
                     /db_xref="GOA:L7N5I2"
                     /db_xref="InterPro:IPR002539"
                     /db_xref="InterPro:IPR003965"
                     /db_xref="UniProtKB/TrEMBL:L7N5I2"
BEGIN
        1 MTQPSGLKNL LRAAAGALPV VPRTDQLPNR TVTVEELPID PANVAAYAAV TGLRYGNQVP
       61 LTYPFALTFP SVMSLVTGFD FPFAAMGAIH TENHITQYRP IAVTDAVGVR VRAENLREHR
      121 RGLLVDLVTN VSVGNDVAWH QVTTFLHQQR TSLSGEPKPP PQKKPKLPPP AAVLRITPAK
      181 IRRYAAVGGD HNPIHTNPIA AKLFGFPTVI AHGMFTAAAV LANIEARFPD AVRYSVRFAK
      241 PVLLPATAGL YVAEGDGGWD LTLRNMAKGY PHLTATVRGL
//