LOCUS       AJF01563.1               537 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative fatty-acid-
            CoA ligase FadD4 (fatty-acid-CoA synthetase) (fatty-acid-
            CoA synthase) protein.
ACCESSION   CP007027-219
PROTEIN_ID  AJF01563.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="fadD4"
                     /locus_tag="Y980_0214"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00455"
                     /note="Rv0214, (MTCY08D5.09) Probable fadD4,fatty-acid-CoA
                     synthetase, similar to many e.g. 4CL_PINTA|P41636
                     4-coumarate--CoA ligase (537 aa). Also similar to others
                     from Mycobacterium tuberculosis e.g. MTCY6A4.14,
                     MTCY493_27, MTCY07A7_11, MTCI28_6. Contains PS00455
                     putative AMP-binding domain signature."
                     /transl_table=11
                     /db_xref="GOA:L7N5T5"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="UniProtKB/TrEMBL:L7N5T5"
BEGIN
        1 MPRGELYKRF RLVMGGIAPC GSGRRAATYP RRMQIRPYIG ADKPAVILYP SGTVISFDEL
       61 EARANRLAHW FRQAGLREDD VVAILMENNE HVHAVMWAAR RSGLYYVPIN THLTASEAAY
      121 IVDNSGAKAI VGSAALRETC HGLAEHLPGG LPDLLMLAGG GLVGWMTYPE CVADQPDTPI
      181 EDEREGDLLQ YSSGTTGRPK GIKRELPHVS PDAAPGMMPA LLDFWMDADS VYLSPAPMYH
      241 TAPSVWTMSA LAAGVTTVVM EKFDAEGALD AIQRYRVTHA QFVPAMFVRM LKLPEAVRNS
      301 YDMSSLRRVI HAAAPCPVQI KEQMIHWWGP IIDEYYASSE ASGSTLITAE DWLTHPGSVG
      361 KPIQGGVHIV GADGSELPPN QPGEIYFEGG YPFEYLNDPA KTAASRNKHG WVTVGDVGYL
      421 DDDGYLFLTG RRHHMIISGG VNIYPQEAEN LLVAHPKVLD AAVFGVPDDE MGQRVMAAVQ
      481 TVDSADANDQ FAGELLAWLR DRLSHFKCPR SIAFEPQLPR TDTGKLYKSG LVEKYSV
//