LOCUS       AJF01525.1               244 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative conserved
            Mce associated membrane protein protein.
ACCESSION   CP007027-181
PROTEIN_ID  AJF01525.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /locus_tag="Y980_0178"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0178, (MTCI28.18) Probable conserved
                     Mce-associated membrane protein, highly similar in
                     C-terminus to CAC32130.1|AL583926 putative secreted
                     protein from Mycobacterium leprae (184 aa). Also similar
                     to mce-associated proteins from Mycobacterium tuberculosis
                     e.g. Rv1363c, Rv0177, Rv1973, etc. Note that there is a 10
                     aa overlap with the upstream ORF. A core mycobacterial
                     gene; conserved in mycobacterial strains (See Marmiesse et
                     al., 2004)."
                     /transl_table=11
                     /db_xref="UniProtKB/TrEMBL:L7N5B1"
BEGIN
        1 MEDQQSASGD LTQKSVANGE STDTASAATE GHRGEIDAAG EPDERGAAVA DSQADEDDSA
       61 ATAARGGKTR ARRSRGRRLA ITVGVAAALF VGSAAFAGAT VEPYLSERAV VATKLMVART
      121 AANAITTLWT YTPENMDTLA DRAANYLSGD FAAQYRRFVD QIAAANKQAK ITNDTEVTGA
      181 AVESLSGRDA VAIVYTNTTT TSPVTKNIPA LKYLSYRLFM KRYDARWLVT RMTTITSLDL
      241 TPQV
//