LOCUS       AJF01520.1               390 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative Mce-family
            lipoprotein LprK (Mce-family lipoprotein Mce1E) protein.
ACCESSION   CP007027-176
PROTEIN_ID  AJF01520.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="lprK"
                     /locus_tag="Y980_0173"
                     /gene_synonym="mce1E"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00013"
                     /note="Rv0173, (MTCI28.13) Possible lprK (alternate gene
                     name: mce1E), lipoprotein which belongs to 24-membered
                     Mycobacterium tuberculosis Mce protein family (see
                     citations below), highly similar to Mycobacterium
                     tuberculosis proteins O07785|LPRL|Rv0593|MTCY19H5.29|mce2E
                     (402 aa); O53971|LPRM|Rv1970|MTV051.08|mce3E (377 aa);
                     etc. Also highly similar to others e.g.
                     NP_302660.1|NC_002677 putative lipoprotein from
                     Mycobacterium leprae (392 aa); CAC12794.1|AL445327
                     putative secreted protein from Streptomyces coelicolor
                     (413 aa); etc. Contains PS00013 prokaryotic membrane
                     lipoprotein lipid attachment site."
                     /transl_table=11
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="UniProtKB/TrEMBL:L0T2R3"
BEGIN
        1 MMSVLARMRV MRHRAWQGLV LLVLALLLSS CGWRGISNVA IPGGPGTGPG SYTIYVQMPD
       61 TLAINGNSRV MVADVWVGSI RAIKLKNWVA TLTLSLKKDV TLPKNATAKI GQTSLLGSQH
      121 VELAAPPDPS PVPLKDGDTI PLKRSSAYPT TEQTLASIAT LLRGGGLVNL EGIQQEINAI
      181 VTGRADQIRA FLGKLDTFTD ELNQQRDDIT RAIDSTNRLL AYVGGRSEVL NRVLTDLPPL
      241 IKHFADKQEL LINASDAVGR LSQSADQYLS AARGDLHQDL QALQCPLKEL RRAAPYLVGA
      301 LKLILTQPFD VDTVPQLVRG DYMNLSLTLD LTYSAIDNAF LTGTGFSGAL RALEQSFGRD
      361 PETMIPDIRY TPNPNDAPGG PLVERGNRQC
//