LOCUS       AJF01518.1               515 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena Mce-family protein
            Mce1C protein.
ACCESSION   CP007027-174
PROTEIN_ID  AJF01518.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="mce1C"
                     /locus_tag="Y980_0171"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0171, (MTCI28.11) Mce1C; belongs to 24-membered
                     Mycobacterium tuberculosis Mce protein family (see
                     citations below), highly similar to Mycobacterium
                     tuberculosis proteins O07787|Rv0591|MTCY19H5.31|mce2C (481
                     aa); O53969|Rv1968|MTV051.06|mce3C (410 aa); etc. Also
                     highly similar to others e.g. NP_302658.1|NC_002677
                     putative secreted protein from Mycobacterium leprae (519
                     aa); CAC12796.1|AL445327 putative secreted protein from
                     Streptomyces coelicolor (351 aa); etc. Weakly similar to
                     downstream ORF Rv0172|MTCI28.12|mce1D (530 aa). Contains
                     possible signal sequence and highly proline-rich
                     C-terminus. Predicted to be an outer membrane protein (See
                     Song et al., 2008)."
                     /transl_table=11
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="InterPro:IPR008360"
                     /db_xref="UniProtKB/TrEMBL:F5BH93"
BEGIN
        1 MRTLEPPNRM RIGLMGIVVA LLVVAVGQSF TSVPMLFAKP SYYGQFTDSG GLHKGDRVRI
       61 AGLGVGTVEG LKIDGDHIVV KFSIGTNTIG TESRLAIRTD TILGRKVLEI EPRGAQALPP
      121 GGVLPVGQST TPYQIYDAFF DVTKAASGWD IETVKRSLNV LSETVDQTYP HLSAALDGVA
      181 KFSDTIGKRD EQITHLLAQA NQVASILGDR SEQVDRLLVN AKTLIAAFNE RGRAVDALLG
      241 NISAFSAQVQ NLINDNPNLN HVLEQLRILT DLLVDRKEDL AETLTILGRF SASFGETFAS
      301 GPYFKVLLAN LVPGQILQPF VDAAFKKRGI SPEDFWRSAG LPAYRWPDPN GTRFPNGAPP
      361 PPPPVLEGTP EHPGPAVPPG SPCSYTPPAD GLPRPWDPLP CANLTQGPFG GPDFPAPLDV
      421 ATSPPNPDGP PPAPGLPIAG RPGEVPPNVP GTPVPIPQEA PPGARTLPLG PAPGPAPPPA
      481 APGPPAPPGP GPQLPAPFIN PGGTGGSGVT GGSEN
//